(2S,3S,4R)-3-O-acetyl-1-O-tert-butyldiphenylsilyl-4-O-succinoyl-2-octadecanoylamino-octadecane

Base Information

• Chemical Name: (2S,3S,4R)-3-O-acetyl-1-O-tert-butyldiphenylsilyl-4-O-succinoyl-2-octadecanoylamino-octadecane
• CAS No.: 1046791-17-6
• Molecular Formula: C₅₈H₉₇NO₈Si
• Molecular Weight: 964.496
• Mol file: 1046791-17-6.mol

Synonyms:(2S,3S,4R)-3-O-acetyl-1-O-tert-butyldiphenylsilyl-4-O-succinoyl-2-octadecanoylamino-octadecane

Chemical Property of (2S,3S,4R)-3-O-acetyl-1-O-tert-butyldiphenylsilyl-4-O-succinoyl-2-octadecanoylamino-octadecane

Chemical Property:

Purity/Quality:

Safty Information:

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• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (2S,3S,4R)-3-O-acetyl-1-O-tert-butyldiphenylsilyl-4-O-succinoyl-2-octadecanoylamino-octadecane

There total 1 articles about (2S,3S,4R)-3-O-acetyl-1-O-tert-butyldiphenylsilyl-4-O-succinoyl-2-octadecanoylamino-octadecane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 40.0%

succinic acid anhydride (108-30-5) + (2S,3S,4R)-1-O-tert-butyldiphenylsilyl-2-octadecanoylamino-octadecane (916596-72-0) + acetic anhydride (108-24-7) → (2S,3S,4R)-3-O-acetyl-1-O-tert-butyldiphenylsilyl-4-O-succinoyl-2-octadecanoylamino-octadecane (1046791-17-6) + C60H99NO10Si (1092062-69-5)

Guidance literature:

succinic acid anhydride; (2S,3S,4R)-1-O-tert-butyldiphenylsilyl-2-octadecanoylamino-octadecane; With pyridine; at 0 - 40 ℃;

acetic anhydride; With pyridine; at 0 - 40 ℃;

DOI:10.1016/j.carres.2008.05.007

Reference yield: 76.0%

phenyl 2-O-benzoyl-3-O-4-methoxybenzyl-1-thio-β-D-glucopyranoside (1046791-07-4) + (2S,3S,4R)-3-O-acetyl-1-O-tert-butyldiphenylsilyl-4-O-succinoyl-2-octadecanoylamino-octadecane (1046791-17-6) → phenyl 6-O-[{(2S,3S,4R)-3-O-acetyl-1-O-tertbutyldiphenylsilyl-2-octadecanoylamino-octadecane-4-yloxy}carbonylpropanoyl]-2-O-benzoyl-3-O-p-methoxybenzyl-1-thio-β-D-glucopyranoside (1046791-31-4)

Guidance literature:

With dmap; 2,4,6-trichlorobenzoyl chloride; triethylamine; In dichloromethane; at 20 ℃; for 2h;

DOI:10.1016/j.carres.2008.05.007

upstream raw materials:

succinic acid anhydride

(2S,3S,4R)-1-O-tert-butyldiphenylsilyl-2-octadecanoylamino-octadecane

acetic anhydride

Downstream raw materials:

phenyl 6-O-[{(2S,3S,4R)-3-O-acetyl-1-O-tertbutyldiphenylsilyl-2-octadecanoylamino-octadecane-4-yloxy}carbonylpropanoyl]-2-O-benzoyl-3-O-p-methoxybenzyl-1-thio-β-D-glucopyranoside