(2-Formyl-phenyl)-carbamic acid, ethyl ester

Base Information

Chemical Name:(2-Formyl-phenyl)-carbamic acid, ethyl ester
CAS No.:50609-24-0
Molecular Formula:C₁₀H₁₁NO₃
Molecular Weight:193.202
Hs Code.:
DSSTox Substance ID:DTXSID901300387

Synonyms:ethyl (2-formylphenyl)carbamate;ethyl N-(2-formylphenyl)carbamate;(2-Formyl-phenyl)-carbamic acid, ethyl ester;GMSLCMSWSLDWQS-UHFFFAOYSA-N;DTXSID901300387;50609-24-0

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (2-Formyl-phenyl)-carbamic acid, ethyl ester

Chemical Property:

XLogP3:1.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:4
Exact Mass:193.07389321
Heavy Atom Count:14
Complexity:206

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCOC(=O)NC1=CC=CC=C1C=O

Technology Process of (2-Formyl-phenyl)-carbamic acid, ethyl ester

There total 5 articles about (2-Formyl-phenyl)-carbamic acid, ethyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 81.0%

: 541-41-3
chloroformic acid ethyl ester

: 552-89-6
2-nitro-benzaldehyde

: 50609-24-0
ethyl (2-formylphenyl)carbamate

Guidance literature:: With tin; ammonium chloride; In methanol; at 25 ℃; for 3.5h; Sonication;
DOI:10.1055/s-2002-25338

Reference yield:

: 42250-17-9
ethyl N-[2-(hydroxymethyl)phenyl]carbamate

: 50609-24-0
ethyl (2-formylphenyl)carbamate

Guidance literature:: With pyridinium chlorochromate; In dichloromethane; at 20 ℃; for 2.5h; diastereoselective reaction;
DOI:10.1021/acs.orglett.8b00237

Reference yield:

: 5344-90-1
2-Aminobenzyl alcohol

: 50609-24-0
ethyl (2-formylphenyl)carbamate

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate / tetrahydrofuran; water / 3 h / 0 - 20 °C

2: pyridinium chlorochromate / dichloromethane / 2.5 h / 20 °C

With potassium carbonate; pyridinium chlorochromate; In tetrahydrofuran; dichloromethane; water;
DOI:10.1021/acs.orglett.8b00237