N,N'-diacetylchitobiosyl allosamizoline

Base Information

• Chemical Name: N,N'-diacetylchitobiosyl allosamizoline
• CAS No.: 153322-50-0
• Molecular Formula: C₂₅H₄₂N₄O₁₄
• Molecular Weight: 622.627
• Mol file: 153322-50-0.mol

Synonyms:b-D-Glucopyranoside,2-(dimethylamino)-3a,5,6,6a-tetrahydro-4-hydroxy-6-(hydroxymethyl)-4H-cyclopentoxazol-5-yl2-(acetylamino)-4-O-[2-(acetylamino)-2-deoxy-b-D-glucopyranosyl]-2-deoxy-, [3aR-(3aa,4a,5b,6a,6aa)]-; 4H-Cyclopentoxazole, b-D-glucopyranoside deriv.

Chemical Property of N,N'-diacetylchitobiosyl allosamizoline

Chemical Property:

• Boiling Point: °Cat760mmHg
• Flash Point: °C
• Density: 1.78g/cm³

Purity/Quality:

95% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of N,N'-diacetylchitobiosyl allosamizoline

There total 60 articles about N,N'-diacetylchitobiosyl allosamizoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

(3aR,4R,5R,6S,6aS)-6-<(Benzyloxy)methyl>-2-(dimethylamino)-3a,5,6,6a-tetrahydro-4-hydroxy-4H-cyclopentoxazol-5-yl 2-acetamido-4-O-(2-acetamido-3-O-benzyl-4,6-O-benzylidene-2-deoxy-β-D-allopyranosyl)-3,6-di-O-benzyl-2-deoxy-β-D-allopyranoside (136773-88-1) → allosamidin (144539-85-5,103782-08-7,153322-50-0)

Guidance literature:

With hydrogen; acetic acid; palladium on activated charcoal; In methanol; under 5250.4 Torr;

DOI:10.1039/c39910001099

Reference yield: 93.0%

(1S,5R)-8-exo-benzyloxymethyl-3-dimethylamino-6-exo-hydroxy-2-oxa-4-azabicyclo<3.3.0>oct-3-en-7-endo-yl 2-acetamido-4-O-(2-acetamido-3-O-benzyl-4,6-O-benzylidene-2-deoxy-β-D-allopyranosyl)-3,6-di-O-benzyl-2-deoxy-β-D-allopyranoside → allosamidin (144539-85-5,103782-08-7,153322-50-0)

Guidance literature:

With hydrogen; palladium on activated charcoal; for 96h; under 2844.3 Torr;

Reference yield: 79.0%

(3aS,4R,5R,6S,6aS)-4-Acetoxy-6-(acetoxymethyl)-2-(dimethylamino)-3a,5,6,6a-tetrahydro-4H-cyclopentoxazol-5-yl 2-acetamido-4-O-(2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-β-D-allopyranosyl)-3,6-di-O-acetyl-2-deoxy-β-D-allopyranoside (114621-74-8,136845-49-3) → allosamidin (144539-85-5,103782-08-7,153322-50-0)

Guidance literature:

With ammonia; In methanol; for 72h; Ambient temperature;

DOI:10.1021/ja960526c

upstream raw materials:

D-Glucose

(3aS,4R,5R,6S,6aS)-4-Acetoxy-6-(acetoxymethyl)-2-(dimethylamino)-3a,5,6,6a-tetrahydro-4H-cyclopentoxazol-5-yl 2-acetamido-4-O-(2-acetamido-3,4,6-tri-O-acetyl-2-deoxy-β-D-allopyranosyl)-3,6-di-O-acetyl-2-deoxy-β-D-allopyranoside

(3aR,4R,5R,6S,6aS)-6-<(Benzyloxy)methyl>-2-(dimethylamino)-3a,5,6,6a-tetrahydro-4-hydroxy-4H-cyclopentoxazol-5-yl 2-acetamido-4-O-(2-acetamido-3-O-benzyl-4,6-O-benzylidene-2-deoxy-β-D-allopyranosyl)-3,6-di-O-benzyl-2-deoxy-β-D-allopyranoside

3,6-di-O-benzyl-(-)-allosamizoline

Downstream raw materials:

(1S,5R)-3-dimethylamino-6-exo-hydroxy-8-exo-hydroxymethyl-2-oxa-4-azabicyclo<3.3.0>oct-3-en-7-endo-yl 2-acetamido-2-deoxy-β-D-allopyranoside

(+/-)-3aS,6aS-dihydro-5R,6S-dihydroxy-2-(dimethylamino)-4S-(hydroxymethyl)cyclopentano<4,3-d>oxazole

D-glucosamine hydrochloride