C₄₉H₇₃NO₆

Base Information

• Chemical Name: C₄₉H₇₃NO₆
• CAS No.: 1392113-42-6
• Molecular Formula: C₄₉H₇₃NO₆
• Molecular Weight: 772.122
• Mol file: 1392113-42-6.mol

Synonyms:C₄₉H₇₃NO₆

Chemical Property of C₄₉H₇₃NO₆

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₄₉H₇₃NO₆

There total 7 articles about C₄₉H₇₃NO₆ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

C50H75NO6 (1392113-41-5) → C49H73NO6 (1392113-42-6)

Guidance literature:

C₅₀H₇₅NO₆; With lithium hydroxide; In 1,4-dioxane; at 63 ℃; for 4h; Inert atmosphere;

With water; trifluoroacetic acid; In methanol;

Reference yield:

betulin (473-98-3) → C49H73NO6 (1392113-42-6)

Guidance literature:

Multi-step reaction with 8 steps

1.1: pyridine / dmap / 50 °C / Inert atmosphere

1.2: 5 h / 50 °C

2.1: pyridinium chlorochromate / dichloromethane / 7.25 h / 20 °C / Inert atmosphere

3.1: potassium hexamethylsilazane / tetrahydrofuran / 0.25 h / -78 °C / Inert atmosphere

3.2: 4.5 h / -78 °C

4.1: sodium carbonate monohydrate / tetrakis(triphenylphosphine) palladium⁽⁰⁾ / isopropyl alcohol; 1,4-dioxane; water / 3.5 h / Inert atmosphere

5.1: water; lithium hydroxide monohydrate / 1,4-dioxane / 25.5 h / 75 °C / Inert atmosphere

6.1: pyridinium chlorochromate / dichloromethane / 6.5 h / 20 °C / Inert atmosphere

7.1: acetic acid / 1,2-dichloro-ethane / 0.17 h / 20 °C / Inert atmosphere

7.2: 48 h / 20 °C

8.1: lithium hydroxide / 1,4-dioxane / 4 h / 63 °C / Inert atmosphere

8.2: YMC Combiprep ODS 30x50 mm S₅

With pyridine; sodium carbonate monohydrate; lithium hydroxide monohydrate; water; potassium hexamethylsilazane; acetic acid; pyridinium chlorochromate; lithium hydroxide; dmap; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In tetrahydrofuran; 1,4-dioxane; dichloromethane; water; 1,2-dichloro-ethane; isopropyl alcohol; 4.1: Suzuki Coupling;

Reference yield:

((1R,3aS,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-9-hydroxy-5a,5b,8,8,11a-pentamethyl-1-(prop-1-en-2-yl)icosahydro-1H-cyclopenta[a]chrysen-3a-yl)methyl benzoate (1350915-24-0) → C49H73NO6 (1392113-42-6)

Guidance literature:

Multi-step reaction with 7 steps

1.1: pyridinium chlorochromate / dichloromethane / 7.25 h / 20 °C / Inert atmosphere

2.1: potassium hexamethylsilazane / tetrahydrofuran / 0.25 h / -78 °C / Inert atmosphere

2.2: 4.5 h / -78 °C

3.1: sodium carbonate monohydrate / tetrakis(triphenylphosphine) palladium⁽⁰⁾ / isopropyl alcohol; 1,4-dioxane; water / 3.5 h / Inert atmosphere

4.1: water; lithium hydroxide monohydrate / 1,4-dioxane / 25.5 h / 75 °C / Inert atmosphere

5.1: pyridinium chlorochromate / dichloromethane / 6.5 h / 20 °C / Inert atmosphere

6.1: acetic acid / 1,2-dichloro-ethane / 0.17 h / 20 °C / Inert atmosphere

6.2: 48 h / 20 °C

7.1: lithium hydroxide / 1,4-dioxane / 4 h / 63 °C / Inert atmosphere

7.2: YMC Combiprep ODS 30x50 mm S₅

With sodium carbonate monohydrate; lithium hydroxide monohydrate; water; potassium hexamethylsilazane; acetic acid; pyridinium chlorochromate; lithium hydroxide; tetrakis(triphenylphosphine) palladium⁽⁰⁾; In tetrahydrofuran; 1,4-dioxane; dichloromethane; water; 1,2-dichloro-ethane; isopropyl alcohol; 3.1: Suzuki Coupling;

upstream raw materials:

betulin

((1R,3aS,5aR,5bR,7aR,9S,11aR,11bR,13aR,13bR)-9-hydroxy-5a,5b,8,8,11a-pentamethyl-1-(prop-1-en-2-yl)icosahydro-1H-cyclopenta[a]chrysen-3a-yl)methyl benzoate

((1R,3aS,5aR,5bR,7aR,11aR,11bR,13aR,13bR)-5a,5b,8,8,11a-Pentamethyl-9-oxo-1-(prop-1-en-2-yl)icosahydro-1H-cyclopenta[a]chrysen-3a-yl)methyl benzoate

((1R,3aS,5aR,5bR,7aR,11aR,11bR,13aR,13bR)-5a,5b,8,8,11a-pentamethyl-1-(prop-1-en-2-yl)-9-(trifluoromethylsulfonyloxy)-2,3,3a,4,5,5a,5b,6,7,7a,8,11,11a,11b,12,13,13a,13b-octadecahydro-1H-cyclopenta[a]chrysen-3a-yl)methyl benzoate