(2-butylbenzofuran-3-yl)(4-(2-(diethylamino)ethoxy)-3,5-bis(trifluoromethyl)phenyl)methanone

Base Information

Chemical Name:(2-butylbenzofuran-3-yl)(4-(2-(diethylamino)ethoxy)-3,5-bis(trifluoromethyl)phenyl)methanone
CAS No.:1469440-79-6
Molecular Formula:C₂₇H₂₉F₆NO₃
Molecular Weight:529.523
Hs Code.:

Synonyms:(2-butylbenzofuran-3-yl)(4-(2-(diethylamino)ethoxy)-3,5-bis(trifluoromethyl)phenyl)methanone

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (2-butylbenzofuran-3-yl)(4-(2-(diethylamino)ethoxy)-3,5-bis(trifluoromethyl)phenyl)methanone

Chemical Property:

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Technology Process of (2-butylbenzofuran-3-yl)(4-(2-(diethylamino)ethoxy)-3,5-bis(trifluoromethyl)phenyl)methanone

There total 4 articles about (2-butylbenzofuran-3-yl)(4-(2-(diethylamino)ethoxy)-3,5-bis(trifluoromethyl)phenyl)methanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: C₂₁H₁₆F₆O₃

: 100-35-6
2-(diethylamino)ethyl chloride

: 1469440-79-6
(2-butylbenzofuran-3-yl)(4-(2-(diethylamino)ethoxy)-3,5-bis(trifluoromethyl)phenyl)methanone

Guidance literature:: With potassium carbonate; sodium iodide; In water; toluene; at 100 ℃; for 0.75h;

Reference yield:

: 1469441-24-4
4-(2-butylbenzofuran-3-carbonyl)-2,6-bis(trifluoromethyl)phenyl acetate

: 1469440-79-6
(2-butylbenzofuran-3-yl)(4-(2-(diethylamino)ethoxy)-3,5-bis(trifluoromethyl)phenyl)methanone

Guidance literature:: Multi-step reaction with 2 steps

1: potassium carbonate; methanol / 1 h / 23 °C

2: potassium carbonate; sodium iodide / toluene; water / 0.75 h / 100 °C

With methanol; potassium carbonate; sodium iodide; In water; toluene;

Reference yield:

: 1951-26-4
2-n-butyl-3-(3',5'-diiodo-4'-hydroxybenzoyl)benzofuran

: 1469440-79-6
(2-butylbenzofuran-3-yl)(4-(2-(diethylamino)ethoxy)-3,5-bis(trifluoromethyl)phenyl)methanone

Guidance literature:: Multi-step reaction with 4 steps

1: pyridine; dmap / 0.67 h / 23 °C

2: copper(l) iodide / N,N-dimethyl-formamide / 0.67 h / 80 °C / Inert atmosphere

3: potassium carbonate; methanol / 1 h / 23 °C

4: potassium carbonate; sodium iodide / toluene; water / 0.75 h / 100 °C

With pyridine; methanol; dmap; copper(l) iodide; potassium carbonate; sodium iodide; In water; N,N-dimethyl-formamide; toluene;