GRI 378898

Base Information

Chemical Name:GRI 378898
CAS No.:2805-76-7
Molecular Formula:C₁₃H₁₀FNO
Molecular Weight:215.227
Hs Code.:

Synonyms:GRI 378898

Suppliers and Price of GRI 378898

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of GRI 378898

Chemical Property:

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Technology Process of GRI 378898

There total 1 articles about GRI 378898 which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 446-52-6
2-Fluorobenzaldehyde

: 95-55-6
2-amino-phenol

: 2805-76-7
GRI 378898

Guidance literature:: DOI:10.1021/ja01516a001

Reference yield: 90.0%

: 2805-76-7
GRI 378898

: C₁₆H₂₁BF₂O₅S

: 3,3-difluoro-4-(2-fluorophenyl)-4-((2-hydroxyphenyl)amino)but-1-en-2-yl 4-methylbenzenesulfonate

Guidance literature:: With methanol; In tetrahydrofuran; at 20 ℃; for 24h; regioselective reaction;
DOI:10.1039/c8ob00541a

Reference yield: 87.0%

: 2805-76-7
GRI 378898

: 24850-33-7
allyltributylstanane

: (S)-2-(1-(2-fluorophenyl)but-3-enylamino)phenol

Guidance literature:: With (NHC₄H₇C(C₆H₃(CH₃)2)2O)BC₆H₅⁽¹⁺⁾*O₃SCF₃^(1-)=[(NHC₄H₇C(C₆H₃(CH₃)2)2O)BC₆H₅](O₃SCF₃); In toluene; at -40 ℃; for 3h; enantioselective reaction; Inert atmosphere;
DOI:10.1021/acs.orglett.9b02280