[1R,4aβ,(+)]-Decahydro-1α,8aα-dimethyl-7β-(1-methylethyl)naphthalene

Base Information

• Chemical Name: [1R,4aβ,(+)]-Decahydro-1α,8aα-dimethyl-7β-(1-methylethyl)naphthalene
• CAS No.: 15404-63-4
• Molecular Formula: C₁₅H₂₈
• Molecular Weight: 208.387
• Hs Code.: 2902199090
• Mol file: 15404-63-4.mol

Synonyms:4bH,5a-Eremophilane (8CI); Naphthalene,decahydro-1,8a-dimethyl-7-(1-methylethyl)-, [1R-(1a,4ab,7b,8aa)]-; Nootkatane (7CI); (+)-Nootkatane; Nootkatane,(+)-

Chemical Property of [1R,4aβ,(+)]-Decahydro-1α,8aα-dimethyl-7β-(1-methylethyl)naphthalene

Chemical Property:

• Vapor Pressure: 0.0208mmHg at 25°C
• Boiling Point: 259.6°C at 760 mmHg
• Flash Point: 103.7°C
• PSA: 0.00000
• Density: 0.849g/cm³
• LogP: 4.88500

Purity/Quality:

99% ^*data from raw suppliers

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of [1R,4aβ,(+)]-Decahydro-1α,8aα-dimethyl-7β-(1-methylethyl)naphthalene

There total 74 articles about [1R,4aβ,(+)]-Decahydro-1α,8aα-dimethyl-7β-(1-methylethyl)naphthalene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 85.0%

(4aR,5S,8aR)-3,4a,5-Trimethyl-4,4a,5,6,7,8,8a,9-octahydro-naphtho[2,3-b]thiophene (113729-71-8) → Eremophilan (3242-05-5,5090-65-3,15404-63-4,20479-35-0,20479-55-4,29788-43-0,35730-77-9,121785-98-6,121785-99-7)

Guidance literature:

W-7-Ra-Ni; In hexane;

DOI:10.1016/S0040-4039(00)96248-8

Reference yield:

Methyltriphenylphosphonium bromide (1779-49-3) + 1-((4aR,8S,8aR)-8,8a-Dimethyl-1,4,4a,5,6,7,8,8a-octahydro-naphthalen-2-yl)-ethanone → α-eremophilane (3242-05-5,5090-65-3,15404-63-4,20479-35-0,20479-55-4,29788-43-0,35730-77-9,121785-98-6,121785-99-7)

Guidance literature:

1-((4aR,8S,8aR)-8,8a-Dimethyl-1,4,4a,5,6,7,8,8a-octahydro-naphthalen-2-yl)-ethanone; With hydrogen; palladium on activated charcoal; In ethyl acetate; for 0.166667h;

Methyltriphenylphosphonium bromide; With n-butyllithium; In tetrahydrofuran; hexane; at 20 ℃; for 0.5h;

With hydrogen; palladium on activated charcoal; In ethyl acetate; for 0.166667h;

DOI:10.1021/jo049431g

Reference yield:

(+)-Eremophilen-(11) → 7-β-eremophilane (3242-05-5,5090-65-3,15404-63-4,20479-35-0,20479-55-4,29788-43-0,35730-77-9,121785-98-6,121785-99-7)

Guidance literature:

With hydrogen; platinum(IV) oxide; In ethanol;

DOI:10.1139/v69-015

upstream raw materials:

valencene

4,5-di-epi-aristolochene

(4aR,5S,8aR)-3,4a,5-Trimethyl-4,4a,5,6,7,8,8a,9-octahydro-naphtho[2,3-b]thiophene

(4aR,8S,8aR)-8,8a-Dimethyl-octahydro-isochromen-3-one