C₁₆H₁₆BrFO₂

Base Information

Chemical Name:C₁₆H₁₆BrFO₂
CAS No.:1426659-16-6
Molecular Formula:C₁₆H₁₆BrFO₂
Molecular Weight:339.204
Hs Code.:

C<sub>16</sub>H<sub>16</sub>BrFO<sub>2</sub>

Synonyms:C₁₆H₁₆BrFO₂

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Chemical Property of C₁₆H₁₆BrFO₂

Chemical Property:

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Technology Process of C₁₆H₁₆BrFO₂

There total 8 articles about C₁₆H₁₆BrFO₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

: 1426659-11-1
C₁₆H₁₄BrFO₂

: 1426659-16-6
C₁₆H₁₆BrFO₂

Guidance literature:: With C₆₇H₇₀Cl₂N₂O₆Ru; potassium tert-butylate; hydrogen; In isopropyl alcohol; under 5171.62 Torr; stereoselective reaction;
DOI:10.1055/s-0032-1317704

Reference yield:

: 1426659-11-1
C₁₆H₁₄BrFO₂

: 1426659-16-6
C₁₆H₁₆BrFO₂

: C₁₆H₁₆BrFO₂

Guidance literature:: With C₆₇H₇₀Cl₂N₂O₆Ru; potassium tert-butylate; hydrogen; In isopropyl alcohol; under 2325.23 Torr; stereoselective reaction;
DOI:10.1055/s-0032-1317704

Reference yield:

: 883514-21-4
2-(5-bromo-2-fluoro-phenyl)acetic acid

: 1426659-16-6
C₁₆H₁₆BrFO₂

Guidance literature:: Multi-step reaction with 4 steps

1: N,N-dimethyl-formamide; oxalyl dichloride / dichloromethane

2: aluminum (III) chloride / dichloromethane / -5 - 23 °C

3: sodium hydride / N,N-dimethyl-formamide

4: C₆₇H₇₀Cl₂N₂O₆Ru; hydrogen; potassium tert-butylate / isopropyl alcohol / 5171.62 Torr

With aluminum (III) chloride; oxalyl dichloride; C₆₇H₇₀Cl₂N₂O₆Ru; potassium tert-butylate; hydrogen; sodium hydride; N,N-dimethyl-formamide; In dichloromethane; N,N-dimethyl-formamide; isopropyl alcohol; 2: |Friedel-Crafts Acylation;
DOI:10.1055/s-0032-1317704