(E)-diethyl 2-(4-fluorostyryl)-6-methylbenzofuro[5,6-b]furan-3,7-dicarboxylate

Base Information

Chemical Name:(E)-diethyl 2-(4-fluorostyryl)-6-methylbenzofuro[5,6-b]furan-3,7-dicarboxylate
CAS No.:1387444-70-3
Molecular Formula:C₂₅H₂₁FO₆
Molecular Weight:436.437
Hs Code.:

Synonyms:(E)-diethyl 2-(4-fluorostyryl)-6-methylbenzofuro[5,6-b]furan-3,7-dicarboxylate

Suppliers and Price of (E)-diethyl 2-(4-fluorostyryl)-6-methylbenzofuro[5,6-b]furan-3,7-dicarboxylate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Total 1 raw suppliers

Chemical Property of (E)-diethyl 2-(4-fluorostyryl)-6-methylbenzofuro[5,6-b]furan-3,7-dicarboxylate

Chemical Property:

Purity/Quality:: 98% ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

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Technology Process of (E)-diethyl 2-(4-fluorostyryl)-6-methylbenzofuro[5,6-b]furan-3,7-dicarboxylate

There total 4 articles about (E)-diethyl 2-(4-fluorostyryl)-6-methylbenzofuro[5,6-b]furan-3,7-dicarboxylate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: diethyl 2-(4-fluorostyryl)-6-methylbenzofuro[5,6-b]furan-3,7-dicarboxylate

: 1387444-70-3
(E)-diethyl 2-(4-fluorostyryl)-6-methylbenzofuro[5,6-b]furan-3,7-dicarboxylate

Guidance literature:: With iodine; In para-xylene; for 4h; Inert atmosphere; Reflux;
DOI:10.1016/j.tetlet.2012.05.087

Reference yield:

: 1387444-64-5
((3,7-bis(ethoxycarbonyl)-6-methylbenzofuro[5,6-b]furan-2-yl)methyl)triphenylphosphonium bromide

: 1387444-70-3
(E)-diethyl 2-(4-fluorostyryl)-6-methylbenzofuro[5,6-b]furan-3,7-dicarboxylate

Guidance literature:: Multi-step reaction with 2 steps

1.1: lithium hydroxide monohydrate / isopropyl alcohol / 0.17 h / 20 °C / Inert atmosphere

1.2: 2.5 h / Inert atmosphere; Reflux

2.1: iodine / para-xylene / 4 h / Inert atmosphere; Reflux

With lithium hydroxide monohydrate; iodine; In para-xylene; isopropyl alcohol; 1.1: Wittig reaction / 1.2: Wittig reaction;
DOI:10.1016/j.tetlet.2012.05.087

Reference yield:

: 1387444-63-4
diethyl 2-(bromomethyl)-6-methylbenzofuro[5,6-b]furan-3,7-dicarboxylate

: 1387444-70-3
(E)-diethyl 2-(4-fluorostyryl)-6-methylbenzofuro[5,6-b]furan-3,7-dicarboxylate

Guidance literature:: Multi-step reaction with 3 steps

1.1: toluene / 2.5 h / Inert atmosphere; Reflux

2.1: lithium hydroxide monohydrate / isopropyl alcohol / 0.17 h / 20 °C / Inert atmosphere

2.2: 2.5 h / Inert atmosphere; Reflux

3.1: iodine / para-xylene / 4 h / Inert atmosphere; Reflux

With lithium hydroxide monohydrate; iodine; In para-xylene; isopropyl alcohol; toluene; 2.1: Wittig reaction / 2.2: Wittig reaction;
DOI:10.1016/j.tetlet.2012.05.087