(4-(tert-butoxycarbonylamino)but-2-enyl)carbamic acid tert-butyl ester

Base Information

• Chemical Name: (4-(tert-butoxycarbonylamino)but-2-enyl)carbamic acid tert-butyl ester
• CAS No.: 215167-64-9
• Molecular Formula: C₁₄H₂₆N₂O₄
• Molecular Weight: 286.371
• Mol file: 215167-64-9.mol

Synonyms:(4-(tert-butoxycarbonylamino)but-2-enyl)carbamic acid tert-butyl ester

Chemical Property of (4-(tert-butoxycarbonylamino)but-2-enyl)carbamic acid tert-butyl ester

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of (4-(tert-butoxycarbonylamino)but-2-enyl)carbamic acid tert-butyl ester

There total 3 articles about (4-(tert-butoxycarbonylamino)but-2-enyl)carbamic acid tert-butyl ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

di-tert-butyl dicarbonate (24424-99-5) + (Z)-but-2-ene-1,4-diaminium chloride → (4-(tert-butoxycarbonylamino)but-2-enyl)carbamic acid tert-butyl ester (215167-64-9)

Guidance literature:

With triethylamine; In dichloromethane; at 20 ℃; for 6h; Cooling with ice;

DOI:10.1021/ma300602p

Reference yield: 29.7%

di-tert-butyl dicarbonate (24424-99-5) + cis-1,4-diamino-2-butene (40794-72-7) → (Z)-(4-aminobut-2-en-1-yl) tert-butyl carbamate (167845-56-9,1807939-98-5) + (4-(tert-butoxycarbonylamino)but-2-enyl)carbamic acid tert-butyl ester (215167-64-9)

Guidance literature:

In ethanol; at 20 ℃;

Reference yield:

(Z)-2-Butene (590-18-1) + N-tert-butoxycarbonylprop-2-en-1-amine (78888-18-3) → (4-(tert-butoxycarbonylamino)but-2-enyl)carbamic acid tert-butyl ester (215167-64-9) + (4-(tert-butoxycarbonylamino)but-2-enyl)carbamic acid tert-butyl ester

Guidance literature:

With Grubbs catalyst first generation; In chloroform; at 50 ℃; for 144h;

DOI:10.1139/v01-045

upstream raw materials:

(Z)-2-Butene

N-tert-butoxycarbonylprop-2-en-1-amine

di-tert-butyl dicarbonate

cis-1,4-diamino-2-butene