N₃-((1-(2-(4-hydroxyphenyl)ethyl)hexahydro-4-pyridinyl)methyl)-2-methyl-2H-3-indazolecarboxamide

Base Information

• Chemical Name: N₃-((1-(2-(4-hydroxyphenyl)ethyl)hexahydro-4-pyridinyl)methyl)-2-methyl-2H-3-indazolecarboxamide
• CAS No.: 1029644-02-7
• Molecular Formula: C₂₃H₂₈N₄O₂
• Molecular Weight: 392.501

Synonyms:N₃-((1-(2-(4-hydroxyphenyl)ethyl)hexahydro-4-pyridinyl)methyl)-2-methyl-2H-3-indazolecarboxamide

Chemical Property of N₃-((1-(2-(4-hydroxyphenyl)ethyl)hexahydro-4-pyridinyl)methyl)-2-methyl-2H-3-indazolecarboxamide

Chemical Property:

Purity/Quality:

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Technology Process of N₃-((1-(2-(4-hydroxyphenyl)ethyl)hexahydro-4-pyridinyl)methyl)-2-methyl-2H-3-indazolecarboxamide

There total 1 articles about N₃-((1-(2-(4-hydroxyphenyl)ethyl)hexahydro-4-pyridinyl)methyl)-2-methyl-2H-3-indazolecarboxamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

1-(2-(4-hydroxyphenyl)ethyl)-4-piperidinylmethanamine + 2-methyl-2H-indazole-3-carbonyl chloride (181071-92-1) → N3-((1-(2-(4-hydroxyphenyl)ethyl)hexahydro-4-pyridinyl)methyl)-2-methyl-2H-3-indazolecarboxamide (1029644-02-7)

Guidance literature:

In toluene; at 20 ℃; for 18h;

Reference yield:

N3-((1-(2-(4-hydroxyphenyl)ethyl)hexahydro-4-pyridinyl)methyl)-2-methyl-2H-3-indazolecarboxamide (1029644-02-7) → 3N-({1-[2-(4-hydroxyphenyl)ethyl]hexahydro-4-pyridinyl}methyl)-2-methyl-2H-3-indazolecarboxamide hydrochloride (1029643-59-1)

Guidance literature:

With hydrogenchloride; In ethanol; ethyl acetate; at 20 ℃; for 3h;

upstream raw materials:

2-methyl-2H-indazole-3-carbonyl chloride

Downstream raw materials:

3N-({1-[2-(4-hydroxyphenyl)ethyl]hexahydro-4-pyridinyl}methyl)-2-methyl-2H-3-indazolecarboxamide hydrochloride

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