Technology Process of 3-Methoxy-18-methyl-16β-phenylselenyl-1,3,5(10)-oestratrien-17α-ol
There total 3 articles about 3-Methoxy-18-methyl-16β-phenylselenyl-1,3,5(10)-oestratrien-17α-ol which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
sodium tetrahydroborate;
In
ethanol;
1) room temp.; 2) reflux at 20 h;
DOI:10.1002/jlac.198119811106
- Guidance literature:
-
Multi-step reaction with 3 steps
1: methyl lithium / diethyl ether / 4 h / Ambient temperature
2: 79 percent / 4-nitroperbenzoic acid / 1,2-dichloro-ethane; 2-methyl-propan-2-ol / 18 h / Ambient temperature
3: 95 percent / NaBH4 / ethanol / 1) room temp.; 2) reflux at 20 h
With
4-nitroperbenzoic acid; sodium tetrahydroborate; methyllithium;
In
diethyl ether; ethanol; 1,2-dichloro-ethane; tert-butyl alcohol;
DOI:10.1002/jlac.198119811106
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 79 percent / 4-nitroperbenzoic acid / 1,2-dichloro-ethane; 2-methyl-propan-2-ol / 18 h / Ambient temperature
2: 95 percent / NaBH4 / ethanol / 1) room temp.; 2) reflux at 20 h
With
4-nitroperbenzoic acid; sodium tetrahydroborate;
In
ethanol; 1,2-dichloro-ethane; tert-butyl alcohol;
DOI:10.1002/jlac.198119811106
