allyl 2-deoxy-2-trichloroacetamido-3-O-triisopropylsilyl-4,6-O-p-methoxybenzylidene-β-D-galactopyranoside

Base Information

Chemical Name:allyl 2-deoxy-2-trichloroacetamido-3-O-triisopropylsilyl-4,6-O-p-methoxybenzylidene-β-D-galactopyranoside
CAS No.:727991-16-4
Molecular Formula:C₂₈H₄₂Cl₃NO₇Si
Molecular Weight:639.088
Hs Code.:

Synonyms:allyl 2-deoxy-2-trichloroacetamido-3-O-triisopropylsilyl-4,6-O-p-methoxybenzylidene-β-D-galactopyranoside

Suppliers and Price of allyl 2-deoxy-2-trichloroacetamido-3-O-triisopropylsilyl-4,6-O-p-methoxybenzylidene-β-D-galactopyranoside

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of allyl 2-deoxy-2-trichloroacetamido-3-O-triisopropylsilyl-4,6-O-p-methoxybenzylidene-β-D-galactopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of allyl 2-deoxy-2-trichloroacetamido-3-O-triisopropylsilyl-4,6-O-p-methoxybenzylidene-β-D-galactopyranoside

There total 6 articles about allyl 2-deoxy-2-trichloroacetamido-3-O-triisopropylsilyl-4,6-O-p-methoxybenzylidene-β-D-galactopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 79.0%

: 107-18-6
allyl alcohol

: 727991-15-3
p-methylphenyl 2-deoxy-2-trichloroacetamido-3-O-triisopropylsilyl-4,6-O-p-methoxybenzylidene-1-thio-β-D-galactopyranoside

: 727991-16-4
allyl 2-deoxy-2-trichloroacetamido-3-O-triisopropylsilyl-4,6-O-p-methoxybenzylidene-β-D-galactopyranoside

Guidance literature:: With N-iodo-succinimide; trifluorormethanesulfonic acid; 4 A molecular sieve; In dichloromethane; at 0 ℃; for 0.166667h;
DOI:10.1021/ja0484045

Reference yield:

: 13154-24-0
triisopropylsilyl chloride

: 727991-16-4
allyl 2-deoxy-2-trichloroacetamido-3-O-triisopropylsilyl-4,6-O-p-methoxybenzylidene-β-D-galactopyranoside

Guidance literature:: Multi-step reaction with 2 steps

1: 75 percent / imidazole; 4-(dimethylamino)pyridine / dimethylformamide / 16 h

2: 79 percent / N-iodosuccinimide; triflic acid; 4A molecular sieves / CH₂Cl₂ / 0.17 h / 0 °C

With 1H-imidazole; dmap; N-iodo-succinimide; trifluorormethanesulfonic acid; 4 A molecular sieve; In dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/ja0484045

Reference yield:

: 1,3,4,6-tetra-O-acetyl-2-deoxy-2-trichloroacetamido-α/β-D-galactopyranoside

: 727991-16-4
allyl 2-deoxy-2-trichloroacetamido-3-O-triisopropylsilyl-4,6-O-p-methoxybenzylidene-β-D-galactopyranoside

Guidance literature:: Multi-step reaction with 5 steps

1: 0.044 g / BF₃*Et₂O / CH₂Cl₂ / 3 h / 20 °C

2: NaOMe / CH₂Cl₂; methanol / 2 h / 20 °C

3: 13 g / DL-10-camphorsulfonic acid / acetonitrile / 12 h / 20 °C

4: 75 percent / imidazole; 4-(dimethylamino)pyridine / dimethylformamide / 16 h

5: 79 percent / N-iodosuccinimide; triflic acid; 4A molecular sieves / CH₂Cl₂ / 0.17 h / 0 °C

With 1H-imidazole; dmap; N-iodo-succinimide; trifluorormethanesulfonic acid; 4 A molecular sieve; camphor-10-sulfonic acid; boron trifluoride diethyl etherate; sodium methylate; In methanol; dichloromethane; N,N-dimethyl-formamide; acetonitrile;
DOI:10.1021/ja0484045