Technology Process of (5R,6R)-5-tert-butyldimethylsilyloxy-6-methyl-2-cyclohexenone
There total 4 articles about (5R,6R)-5-tert-butyldimethylsilyloxy-6-methyl-2-cyclohexenone which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
(2R,3R,5R)-3-tert-butyldimethylsilyloxy-2-methyl-5-(1-methylethenyl)cyclohexanone;
With
ozone;
In
methanol; dichloromethane;
at -78 ℃;
With
copper(II) acetate monohydrate;
In
methanol; dichloromethane;
at -20 ℃;
for 0.333333h;
With
ferrous(II) sulfate heptahydrate;
In
methanol; dichloromethane;
at -20 - 20 ℃;
for 10h;
DOI:10.1039/c0ob01118e
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: N-acetylcystein; diphenyl diselenide; sodium hydroxide / methanol / 1.5 h / Inert atmosphere
2.1: 1H-imidazole / N,N-dimethyl-formamide / 24 h / 0 - 20 °C
3.1: ozone / methanol; dichloromethane / -78 °C
3.2: 0.33 h / -20 °C
3.3: 10 h / -20 - 20 °C
With
1H-imidazole; N-acetylcystein; diphenyl diselenide; ozone; sodium hydroxide;
In
methanol; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1039/c0ob01118e
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: dihydrogen peroxide; sodium hydroxide / methanol; water / -20 °C
2.1: N-acetylcystein; diphenyl diselenide; sodium hydroxide / methanol / 1.5 h / Inert atmosphere
3.1: 1H-imidazole / N,N-dimethyl-formamide / 24 h / 0 - 20 °C
4.1: ozone / methanol; dichloromethane / -78 °C
4.2: 0.33 h / -20 °C
4.3: 10 h / -20 - 20 °C
With
1H-imidazole; N-acetylcystein; diphenyl diselenide; dihydrogen peroxide; ozone; sodium hydroxide;
In
methanol; dichloromethane; water; N,N-dimethyl-formamide;
DOI:10.1039/c0ob01118e