Technology Process of 9-((2R,4aR,6R,7R,8S,8aS)-8-Nitro-2-phenyl-7-phenylsulfanyl-hexahydro-pyrano[3,2-d][1,3]dioxin-6-yl)-9H-purin-6-ylamine
There total 6 articles about 9-((2R,4aR,6R,7R,8S,8aS)-8-Nitro-2-phenyl-7-phenylsulfanyl-hexahydro-pyrano[3,2-d][1,3]dioxin-6-yl)-9H-purin-6-ylamine which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
potassium fluoride;
In
tetrahydrofuran;
for 2h;
Heating;
- Guidance literature:
-
Multi-step reaction with 4 steps
1: NaOH / H2O
2: 33 percent / zinc chloride / 6 h / Ambient temperature
3: 98 percent / pyridine, acetic anhydride / CH2Cl2 / 2 h / 0 °C / other reagents: methanesulfonic acid, 4-(dimethylamino)pyridine/acetic anhydride
4: 71 percent / potassium fluoride / tetrahydrofuran / 3 h / Heating
With
pyridine; potassium fluoride; sodium hydroxide; acetic anhydride; zinc(II) chloride;
In
tetrahydrofuran; dichloromethane; water;
DOI:10.1080/07328319808004672
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 98 percent / pyridine, acetic anhydride / CH2Cl2 / 2 h / 0 °C / other reagents: methanesulfonic acid, 4-(dimethylamino)pyridine/acetic anhydride
2: 71 percent / potassium fluoride / tetrahydrofuran / 3 h / Heating
With
pyridine; potassium fluoride; acetic anhydride;
In
tetrahydrofuran; dichloromethane;
DOI:10.1080/07328319808004672