9-((2R,4aR,6R,8aS)-8-Nitro-2-phenyl-4,4a,6,8a-tetrahydro-pyrano[3,2-d][1,3]dioxin-6-yl)-9H-purin-6-ylamine

Base Information

Chemical Name:9-((2R,4aR,6R,8aS)-8-Nitro-2-phenyl-4,4a,6,8a-tetrahydro-pyrano[3,2-d][1,3]dioxin-6-yl)-9H-purin-6-ylamine
CAS No.:183051-95-8
Molecular Formula:C₁₈H₁₆N₆O₅
Molecular Weight:396.362
Hs Code.:

Synonyms:9-((2R,4aR,6R,8aS)-8-Nitro-2-phenyl-4,4a,6,8a-tetrahydro-pyrano[3,2-d][1,3]dioxin-6-yl)-9H-purin-6-ylamine

Suppliers and Price of 9-((2R,4aR,6R,8aS)-8-Nitro-2-phenyl-4,4a,6,8a-tetrahydro-pyrano[3,2-d][1,3]dioxin-6-yl)-9H-purin-6-ylamine

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 9-((2R,4aR,6R,8aS)-8-Nitro-2-phenyl-4,4a,6,8a-tetrahydro-pyrano[3,2-d][1,3]dioxin-6-yl)-9H-purin-6-ylamine

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of 9-((2R,4aR,6R,8aS)-8-Nitro-2-phenyl-4,4a,6,8a-tetrahydro-pyrano[3,2-d][1,3]dioxin-6-yl)-9H-purin-6-ylamine

There total 5 articles about 9-((2R,4aR,6R,8aS)-8-Nitro-2-phenyl-4,4a,6,8a-tetrahydro-pyrano[3,2-d][1,3]dioxin-6-yl)-9H-purin-6-ylamine which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 183051-91-4
(2R,4aR,6R,7R,8R,8aS)-6-(6-Amino-purin-9-yl)-8-nitro-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-7-ol

: 183051-95-8
9-((2R,4aR,6R,8aS)-8-Nitro-2-phenyl-4,4a,6,8a-tetrahydro-pyrano[3,2-d][1,3]dioxin-6-yl)-9H-purin-6-ylamine

Guidance literature:: With pyridine; acetic anhydride; In dichloromethane; at 0 ℃; for 2h; other reagents: methanesulfonic acid, 4-(dimethylamino)pyridine/acetic anhydride;
DOI:10.1080/07328319808004672

Reference yield:

: 39798-19-1
Adenosine dialdehyde

: 183051-95-8
9-((2R,4aR,6R,8aS)-8-Nitro-2-phenyl-4,4a,6,8a-tetrahydro-pyrano[3,2-d][1,3]dioxin-6-yl)-9H-purin-6-ylamine

Guidance literature:: Multi-step reaction with 3 steps

1: NaOH / H₂O

2: 33 percent / zinc chloride / 6 h / Ambient temperature

3: 98 percent / pyridine, acetic anhydride / CH₂Cl₂ / 2 h / 0 °C / other reagents: methanesulfonic acid, 4-(dimethylamino)pyridine/acetic anhydride

With pyridine; sodium hydroxide; acetic anhydride; zinc(II) chloride; In dichloromethane; water;
DOI:10.1080/07328319808004672

Reference yield:

: 183051-90-3
(2R,4aR,6R,7S,8R,8aS)-6-(6-Amino-purin-9-yl)-8-nitro-2-phenyl-hexahydro-pyrano[3,2-d][1,3]dioxin-7-ol

: 183051-95-8
9-((2R,4aR,6R,8aS)-8-Nitro-2-phenyl-4,4a,6,8a-tetrahydro-pyrano[3,2-d][1,3]dioxin-6-yl)-9H-purin-6-ylamine

Guidance literature:: Multi-step reaction with 2 steps

1: 80 percent / ammonia / methanol / 2.33 h / 100 °C / other reagent: t-BuOK, other solvent: DMF, other temperature

2: 98 percent / pyridine, acetic anhydride / CH₂Cl₂ / 2 h / 0 °C / other reagents: methanesulfonic acid, 4-(dimethylamino)pyridine/acetic anhydride

With pyridine; ammonia; acetic anhydride; In methanol; dichloromethane;
DOI:10.1080/07328319808004672