Technology Process of N,N'-(2-fluoro-1,4-phenylene)diacetamide
There total 6 articles about N,N'-(2-fluoro-1,4-phenylene)diacetamide which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
Multi-step reaction with 2 steps
1: palladium hydroxide 10 wt. % on activated carbon; hydrogen / ethanol / 12 h / 20 °C / 750.08 Torr / Inert atmosphere
2: sodium acetate / diethyl ether / Inert atmosphere
With
palladium hydroxide 10 wt. % on activated carbon; hydrogen; sodium acetate;
In
diethyl ether; ethanol;
DOI:10.1002/ejoc.201500795
- Guidance literature:
-
Multi-step reaction with 4 steps
1: sodium acetate / water / 1 h / 0 °C / Inert atmosphere
2: sulfuric acid; guanidine nitrate / water / 6 h / -10 °C / Inert atmosphere
3: palladium hydroxide 10 wt. % on activated carbon; hydrogen / ethanol / 12 h / 20 °C / 750.08 Torr / Inert atmosphere
4: sodium acetate / diethyl ether / Inert atmosphere
With
sulfuric acid; palladium hydroxide 10 wt. % on activated carbon; hydrogen; sodium acetate; guanidine nitrate;
In
diethyl ether; ethanol; water;
DOI:10.1002/ejoc.201500795
