(+)-<2R(3E,5R),4S,6S,8R,9S>-2-<6-hydroxy-3,5-dimethyl-2-hexenyl>-8,9-dimethyl-1,7-dioxaspiro<5.5>undecan-4-ol benzoate

Base Information

• Chemical Name: (+)-<2R(3E,5R),4S,6S,8R,9S>-2-<6-hydroxy-3,5-dimethyl-2-hexenyl>-8,9-dimethyl-1,7-dioxaspiro<5.5>undecan-4-ol benzoate
• CAS No.: 127785-57-3
• Molecular Formula: C₂₆H₃₈O₅
• Molecular Weight: 430.585
• Mol file: 127785-57-3.mol

Synonyms:(+)-<2R(3E,5R),4S,6S,8R,9S>-2-<6-hydroxy-3,5-dimethyl-2-hexenyl>-8,9-dimethyl-1,7-dioxaspiro<5.5>undecan-4-ol benzoate

Chemical Property of (+)-<2R(3E,5R),4S,6S,8R,9S>-2-<6-hydroxy-3,5-dimethyl-2-hexenyl>-8,9-dimethyl-1,7-dioxaspiro<5.5>undecan-4-ol benzoate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of (+)-<2R(3E,5R),4S,6S,8R,9S>-2-<6-hydroxy-3,5-dimethyl-2-hexenyl>-8,9-dimethyl-1,7-dioxaspiro<5.5>undecan-4-ol benzoate

There total 2 articles about (+)-<2R(3E,5R),4S,6S,8R,9S>-2-<6-hydroxy-3,5-dimethyl-2-hexenyl>-8,9-dimethyl-1,7-dioxaspiro<5.5>undecan-4-ol benzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

(+)-<2R(2E,4R),4S,6S,8R,9S>-2-<6-(tert-butyldiphenylsilyloxy)-3,5-dimethyl-2-hexenyl>-8,9-dimethyl-1,7-dioxaspiro<5.5>undecan-4-ol benzoate (127785-56-2) → (+)-<2R(3E,5R),4S,6S,8R,9S>-2-<6-hydroxy-3,5-dimethyl-2-hexenyl>-8,9-dimethyl-1,7-dioxaspiro<5.5>undecan-4-ol benzoate (127785-57-3)

Guidance literature:

With tetrabutyl ammonium fluoride; In tetrahydrofuran; Ambient temperature;

DOI:10.1016/S0040-4020(01)89182-1

Reference yield:

(+)-<2R(2E,4R),4S,6S,8R,9S>-2-<6-(tert-butyldiphenylsilyloxy)-3,5-dimethyl-2-hexenyl>-8,9-dimethyl-1,7-dioxaspiro<5.5>undecan-4-ol (109826-76-8) → (+)-<2R(3E,5R),4S,6S,8R,9S>-2-<6-hydroxy-3,5-dimethyl-2-hexenyl>-8,9-dimethyl-1,7-dioxaspiro<5.5>undecan-4-ol benzoate (127785-57-3)

Guidance literature:

Multi-step reaction with 2 steps

1: 4-dimethylaminopyridine / pyridine / 16 h

2: tetrabutylammonium fluoride / tetrahydrofuran / 4 h

With dmap; tetrabutyl ammonium fluoride; In tetrahydrofuran; pyridine;

DOI:10.1016/S0040-4039(00)96834-5

Reference yield: 85.0%

(+)-<2R(3E,5R),4S,6S,8R,9S>-2-<6-hydroxy-3,5-dimethyl-2-hexenyl>-8,9-dimethyl-1,7-dioxaspiro<5.5>undecan-4-ol benzoate (127785-57-3) → (+)-<2R,4E,6(2R,4S,6S,8R,9S)>-6-(4-benzoyloxy-8,9-dimethyl-1,7-dioxaspiro<5.5>undecan-2-yl)-2,4-dimethyl-4-hexenal (115031-05-5)

Guidance literature:

With 4 A molecular sieve; 4-methylmorpholine N-oxide; tetrapropylammonium perruthennate; In dichloromethane; 1.) room temp., 10 min; 2.) 40 min;

DOI:10.1016/S0040-4020(01)89182-1

upstream raw materials:

(+)-<2R(2E,4R),4S,6S,8R,9S>-2-<6-(tert-butyldiphenylsilyloxy)-3,5-dimethyl-2-hexenyl>-8,9-dimethyl-1,7-dioxaspiro<5.5>undecan-4-ol benzoate

(+)-<2R(2E,4R),4S,6S,8R,9S>-2-<6-(tert-butyldiphenylsilyloxy)-3,5-dimethyl-2-hexenyl>-8,9-dimethyl-1,7-dioxaspiro<5.5>undecan-4-ol

Downstream raw materials:

(+)-<2R,4E,6(2R,4S,6S,8R,9S)>-6-(4-benzoyloxy-8,9-dimethyl-1,7-dioxaspiro<5.5>undecan-2-yl)-2,4-dimethyl-4-hexenal

C₄₅H₆₀O₈

C₄₅H₅₈O₉

C₆₁H₇₈O₈Si