3a-Ethoxy-2,4-diphenyl-3a,4,6,7,8,9-hexahydro-3,10-dithia-4,10b-diaza-cyclopenta[a]fluorene-1,5-dione

Base Information

• Chemical Name: 3a-Ethoxy-2,4-diphenyl-3a,4,6,7,8,9-hexahydro-3,10-dithia-4,10b-diaza-cyclopenta[a]fluorene-1,5-dione
• CAS No.: 79587-88-5
• Molecular Formula: C₂₆H₂₄N₂O₃S₂
• Molecular Weight: 476.62
• Mol file: 79587-88-5.mol

Synonyms:3a-Ethoxy-2,4-diphenyl-3a,4,6,7,8,9-hexahydro-3,10-dithia-4,10b-diaza-cyclopenta[a]fluorene-1,5-dione

Chemical Property of 3a-Ethoxy-2,4-diphenyl-3a,4,6,7,8,9-hexahydro-3,10-dithia-4,10b-diaza-cyclopenta[a]fluorene-1,5-dione

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3a-Ethoxy-2,4-diphenyl-3a,4,6,7,8,9-hexahydro-3,10-dithia-4,10b-diaza-cyclopenta[a]fluorene-1,5-dione

There total 3 articles about 3a-Ethoxy-2,4-diphenyl-3a,4,6,7,8,9-hexahydro-3,10-dithia-4,10b-diaza-cyclopenta[a]fluorene-1,5-dione which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 90.0%

ethyl 2-chloro-2-phenylacetate (10606-73-2,99531-04-1,116836-53-4,4773-33-5) + 3-phenyl-2-thioxo-2,3,5,6,7,8-hexahydro-1H-benzo[4,5]thieno[2,3-d]-pyrimidin-4-one (42076-13-1) → 3a-Ethoxy-2,4-diphenyl-3a,4,6,7,8,9-hexahydro-3,10-dithia-4,10b-diaza-cyclopenta[a]fluorene-1,5-dione (79587-88-5)

Guidance literature:

With potassium carbonate; In N,N-dimethyl-formamide; acetone; for 12h; Heating;

Reference yield:

(4-Oxo-3-phenyl-3,4,5,6,7,8-hexahydro-benzo[4,5]thieno[2,3-d]pyrimidin-2-ylsulfanyl)-phenyl-acetic acid (79587-90-9) → 3a-Ethoxy-2,4-diphenyl-3a,4,6,7,8,9-hexahydro-3,10-dithia-4,10b-diaza-cyclopenta[a]fluorene-1,5-dione (79587-88-5)

Guidance literature:

Multi-step reaction with 2 steps

1: Ac₂O, pyridine / 0.08 h / Heating

2: CHCl₃ / 12 h / Heating

With pyridine; acetic anhydride; In chloroform;

Reference yield:

ethanol (64-17-5) + C24H18N2O2S2 → 3a-Ethoxy-2,4-diphenyl-3a,4,6,7,8,9-hexahydro-3,10-dithia-4,10b-diaza-cyclopenta[a]fluorene-1,5-dione (79587-88-5)

Guidance literature:

In chloroform; for 12h; Heating;

upstream raw materials:

ethanol

ethyl 2-chloro-2-phenylacetate

3-phenyl-2-thioxo-2,3,5,6,7,8-hexahydro-1H-benzo[4,5]thieno[2,3-d]-pyrimidin-4-one

(4-Oxo-3-phenyl-3,4,5,6,7,8-hexahydro-benzo[4,5]thieno[2,3-d]pyrimidin-2-ylsulfanyl)-phenyl-acetic acid

Downstream raw materials:

(4-Oxo-3-phenyl-3,4,5,6,7,8-hexahydro-benzo[4,5]thieno[2,3-d]pyrimidin-2-ylsulfanyl)-phenyl-acetic acid