(S)-1--2-phenylethyl phosphonic acid

Base Information

Chemical Name:(S)-1--2-phenylethyl phosphonic acid
CAS No.:107072-63-9
Molecular Formula:C₁₆H₁₈NO₅P
Molecular Weight:335.296
Hs Code.:

(S)-1-<N-(phenylmethoxycarbonyl)amino>-2-phenylethyl phosphonic acid

Synonyms:(S)-1--2-phenylethyl phosphonic acid

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (S)-1--2-phenylethyl phosphonic acid

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Technology Process of (S)-1--2-phenylethyl phosphonic acid

There total 1 articles about (S)-1--2-phenylethyl phosphonic acid which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 92.0%

: 66609-42-5
D-Phenylalanine phosphonate

: 501-53-1,94274-21-2
benzyl chloroformate

: 107072-63-9
(S)-1--2-phenylethyl phosphonic acid

Guidance literature:: With sodium hydroxide; sodium hydrogencarbonate; sodium carbonate; at 21 ℃; for 20h;

Reference yield:

: 107072-63-9
(S)-1--2-phenylethyl phosphonic acid

: 116381-45-4
C₁₆H₁₆Cl₂NO₃P

Guidance literature:: With thionyl chloride; In dichloromethane; at 21 ℃; for 4h;

Reference yield:

: 107072-63-9
(S)-1--2-phenylethyl phosphonic acid

: (S)-1-((4R,6R)-4,6-Dimethyl-2-oxo-2λ⁵-[1,3,2]dioxaphosphinan-2-yl)-2-phenyl-ethylamine

Guidance literature:: Multi-step reaction with 3 steps

1: SOCl₂ / CH₂Cl₂ / 4 h / 21 °C

2: 95 percent / Et₃N / CH₂Cl₂ / 1 h

3: 99 percent / H₂ / 5percent Pd/C / methanol / 4 h

With thionyl chloride; hydrogen; triethylamine; palladium on activated charcoal; In methanol; dichloromethane;