2-(4-bromophenyl)-2,3-dihydrobenzo[d][1,3,2]diazaborinin-4(1H)-one

Base Information

• Chemical Name: 2-(4-bromophenyl)-2,3-dihydrobenzo[d][1,3,2]diazaborinin-4(1H)-one
• CAS No.: 1296939-25-7
• Molecular Formula: C₁₃H₁₀BBrN₂O
• Molecular Weight: 300.95
• Mol file: 1296939-25-7.mol

Synonyms:2-(4-bromophenyl)-2,3-dihydrobenzo[d][1,3,2]diazaborinin-4(1H)-one

Chemical Property of 2-(4-bromophenyl)-2,3-dihydrobenzo[d][1,3,2]diazaborinin-4(1H)-one

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-(4-bromophenyl)-2,3-dihydrobenzo[d][1,3,2]diazaborinin-4(1H)-one

There total 3 articles about 2-(4-bromophenyl)-2,3-dihydrobenzo[d][1,3,2]diazaborinin-4(1H)-one which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

4-Bromophenylboronic acid (5467-74-3) + anthranilic acid amide (28144-70-9,88-68-6) → 2-(4-bromophenyl)-2,3-dihydrobenzo[d][1,3,2]diazaborinin-4(1H)-one (1296939-25-7)

Guidance literature:

In toluene; for 1h; Inert atmosphere; Reflux;

DOI:10.1021/ol200764g

Reference yield: 94.0%

→ 2-(4-bromophenyl)-2,3-dihydrobenzo[d][1,3,2]diazaborinin-4(1H)-one (1296939-25-7)

Guidance literature:

In ethyl acetate; for 3h;

Reference yield: 91.0%

anthranilic acid amide (28144-70-9,88-68-6) + potassium 4-bromophenyltrifluoroborate (374564-35-9) → 2-(4-bromophenyl)-2,3-dihydrobenzo[d][1,3,2]diazaborinin-4(1H)-one (1296939-25-7)

Guidance literature:

With boron trifluoride monoethylamine; In toluene; at 80 ℃; for 16h; Inert atmosphere; Sealed tube;

DOI:10.1021/acs.joc.7b00747

upstream raw materials:

4-Bromophenylboronic acid

anthranilic acid amide

potassium 4-bromophenyltrifluoroborate

Downstream raw materials:

2-{3-(dimethylphenylsilyl)-4'-methyl-[1,1'-biphenyl]-4-yl}-2,3-dihydrobenzo[d][1,3,2]diazaborinin-4(1H)-one

2-(4'-methyl-[1,1'-biphenyl]-4-yl)-2,3-dihydrobenzo[d][1,3,2]diazaborinin-4(1H)-one