ASTROMICINSULFATE

Base Information

Chemical Name:ASTROMICINSULFATE
CAS No.:72275-67-3
Molecular Formula:C₁₇H₃₅N₅O₆*H₂O₄S
Molecular Weight:503.574
Hs Code.:

Synonyms:ASTROMICINSULFATE;2-amino-N-[(1R,2R,3R,4R,5S,6R)-4-amino-3-[(2R,3R,6S)-3-amino-6-(1-amin oethyl)oxan-2-yl]oxy-2,5-dihydroxy-6-methoxy-cyclohexyl]-N-methyl-acet amide: sulfuric acid;Abbott 44747;Fortimicin A disulfate;Fortimicin A sulfate;L-chiro-Inositol, 4-amino-1-[(aminoacetyl)methylamino]-1,4-dideoxy-3-O-(2,6-diamino-2,3,4,6,7-pentadeoxy-β-L-lyxo-heptopyranosyl)-6-O-methyl-, sulfate (1:2) (salt)

Suppliers and Price of ASTROMICINSULFATE

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 8 raw suppliers

Chemical Property of ASTROMICINSULFATE

Chemical Property:

Boiling Point:621.1oC at760mmHg
Flash Point:329.4oC
PSA：192.54000
Density:1.31 g/cm3
LogP:-0.78420

Purity/Quality:: 98%min ^*data from raw suppliers

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:: SDS file from LookChem

Useful:

Description Astromicin sulfate is a pseudodisaccharide aminoglycoside antibiotic with a spectrum comparable to amikacin. It is active against many gentamicin and amikacin resistant bacteria expressing aminoglycoside-modifying enzymes, with the exception of aminoglycoside 3-acetyltransferase.
Therapeutic Function Antibiotic

Technology Process of ASTROMICINSULFATE

There total 21 articles about ASTROMICINSULFATE which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 67010-18-8,71564-66-4,71695-73-3,76420-54-7,76822-45-2,78738-61-1,78821-72-4,79703-13-2
2-epi-fortimicin A tetrahydrochloride

: 66768-12-5,72275-67-3,73285-04-8,78781-03-0,78853-70-0,82731-19-9
2-epi-fortimicin A disulfate

Guidance literature:: With AG₁-X₂ (SO₄^(2-)) resin; In water;
DOI:10.1016/S0008-6215(00)80393-6

Reference yield: 83.0%

: 55779-06-1
fortimicin A

: 66768-12-5,72275-67-3,73285-04-8,78781-03-0,78853-70-0,82731-19-9
fortimicin A sulfate

Guidance literature:

Reference yield:

: 66962-55-8,71658-13-4,76822-42-9,78609-41-3,78781-05-2
1,2',6'-tri-N-benzyloxycarbonyl-2-epi-fortimicin B

: 66768-12-5,72275-67-3,73285-04-8,78781-03-0,78853-70-0,82731-19-9
2-epi-fortimicin A disulfate

Guidance literature:: Multi-step reaction with 4 steps

1: 65 percent / tetrahydrofuran / 72 h / Ambient temperature

2: 76 percent / 5 percent aq. NaHCO₃ / methanol / Ambient temperature

3: 98 percent / H₂, 0.1 M methanolic HCl / 5 percent Pd-C / 4 h / 2280 Torr

4: 84 percent / AG₁-X₂ (SO₄^(2-)) resin / H₂O

With hydrogenchloride; AG₁-X₂ (SO₄^(2-)) resin; hydrogen; sodium hydrogencarbonate; palladium on activated charcoal; In tetrahydrofuran; methanol; water;
DOI:10.1016/S0008-6215(00)80393-6