1-(4-Benzyloxy-3-hydroxymethylphenyl)ethanone

Base Information

Chemical Name:1-(4-Benzyloxy-3-hydroxymethylphenyl)ethanone
CAS No.:39235-59-1
Molecular Formula:C₁₆H₁₆O₃
Molecular Weight:256.301
Hs Code.:
UNII:7FF4YPV39Z
DSSTox Substance ID:DTXSID701214966

Synonyms:4-benzyloxy-3-hydroxymethylacetophenone;39235-59-1;1-[3-(Hydroxymethyl)-4-(phenylmethoxy)phenyl]ethanone;1-(4-Benzyloxy-3-hydroxymethylphenyl)ethanone;7FF4YPV39Z;SCHEMBL10664626;PNEFCQBLUJPRPQ-UHFFFAOYSA-N;DTXSID701214966

Suppliers and Price of 1-(4-Benzyloxy-3-hydroxymethylphenyl)ethanone

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 1-(4-Benzyloxy-3-hydroxymethylphenyl)ethanone

Chemical Property:

XLogP3:2.2
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:3
Rotatable Bond Count:5
Exact Mass:256.109944368
Heavy Atom Count:19
Complexity:284

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CC(=O)C1=CC(=C(C=C1)OCC2=CC=CC=C2)CO

Technology Process of 1-(4-Benzyloxy-3-hydroxymethylphenyl)ethanone

There total 5 articles about 1-(4-Benzyloxy-3-hydroxymethylphenyl)ethanone which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 97.0%

: 39235-58-0
4-hydroxy-3-hydroxymethylacetophenone

: 100-44-7
benzyl chloride

: 39235-59-1
(2-benzyloxy-5-isopropenyl-phenyl)-methanol

Guidance literature:: With potassium carbonate; In acetonitrile; for 4h; Reflux;
DOI:10.1080/10286020.2020.1771700

Reference yield: 84.4%

: 39235-60-4
4'-benzyloxy-3'-acetoxymethylacetophenone

: 39235-59-1
(2-benzyloxy-5-isopropenyl-phenyl)-methanol

Guidance literature:: With sodium hydroxide; In methanol; for 1h; Reflux;

Reference yield:

: 99-93-4
4-Hydroxyacetophenone

: 39235-59-1
(2-benzyloxy-5-isopropenyl-phenyl)-methanol

Guidance literature:: Multi-step reaction with 4 steps

1: hydrogenchloride / water / 5 h / 20 °C

2: 3 h / 100 °C

3: potassium carbonate / N,N-dimethyl-formamide / 12 h / 10 - 30 °C

4: sodium hydroxide / methanol / 1 h / Reflux

With hydrogenchloride; potassium carbonate; sodium hydroxide; In methanol; water; N,N-dimethyl-formamide;