39235-58-0Relevant articles and documents
Synthesis of the impurity F of salbutamol
Song, Shu-Lian,Lian, Cheng-Xi,Chen, Li-Ping,Huang, Long-Liang
, p. 956 - 965 (2020/06/30)
First synthesis of the diastereomeric mixture of salbutamol impurity F is described in seven steps by using 4-hydroxyacetophenone as starting material, with 15.2percent total yield. The synthesis provides access to multi-gram quantities of impurity F with good purity for reference supplies and further analytical and toxicology investigations. (Figure presented.).
5-(1-Acetoxyvinyl)-cyclosaligenyl-2′,3′-dideoxy-2′, 3′- didehydrothymidine monophosphates, a second type of new, enzymatically activated cyclosaligenyl pronucleotides
Gisch, Nicolas,Pertenbreiter, Florian,Balzarini, Jan,Meier, Chris
supporting information; experimental part, p. 8115 - 8123 (2009/12/07)
In our attempt to further develop the cycloSal pronucleotide concept, we report on 5-(1-acetoxyvinyl)-cycloSal-d4TMPs as a new type of enzyme-activated pronucleotides. These compounds were converted into 5-acetyl-cycloSal-d4TMPs by (carboxy)esterase cleav
Synthesis and Insecticidal Activity of Some New 3-Substituted 4-Hydroxyacetophenones
Borthakur, R. C.,Borthakur, N.,Rastogi, R. C.
, p. 244 - 248 (2007/10/02)
A number of 3-(N,N-dialkylaminomethyl)-4-hydroxy acetophenones (4-10) and their thiophosphorylated compounds (11-16) have been synthesised and screened for their insecticidal activity.Only thiophosphorylated compounds are found to possess significant activity.The intramolecular hydrogen bonding in these compounds has also been discussed.