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39235-58-0

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39235-58-0 Usage

Uses

1-[4-Hydroxy-3-(hydroxymethyl)phenyl]-ethanone is an intermediate in synthesizing Albuterol Dimer Ether (A514520), which is an impurity of Albuterol (Salbutamol) (A514500). Albuterol impurity F. Albuterol is a β2-adrenoceptor agonist. Bronchodilator; tocolytic.

Preparation

Obtained by refluxing 3-chloromethyl-4-hydroxy-acetophenone with water for 3 h (70%).

Check Digit Verification of cas no

The CAS Registry Mumber 39235-58-0 includes 8 digits separated into 3 groups by hyphens. The first part of the number,starting from the left, has 5 digits, 3,9,2,3 and 5 respectively; the second part has 2 digits, 5 and 8 respectively.
Calculate Digit Verification of CAS Registry Number 39235-58:
(7*3)+(6*9)+(5*2)+(4*3)+(3*5)+(2*5)+(1*8)=130
130 % 10 = 0
So 39235-58-0 is a valid CAS Registry Number.

39235-58-0SDS

SAFETY DATA SHEETS

According to Globally Harmonized System of Classification and Labelling of Chemicals (GHS) - Sixth revised edition

Version: 1.0

Creation Date: Aug 19, 2017

Revision Date: Aug 19, 2017

1.Identification

1.1 GHS Product identifier

Product name 4-hydroxy-3-hydroxymethylacetophenone

1.2 Other means of identification

Product number -
Other names 4-acetylsalicyl alcohol

1.3 Recommended use of the chemical and restrictions on use

Identified uses For industry use only.
Uses advised against no data available

1.4 Supplier's details

1.5 Emergency phone number

Emergency phone number -
Service hours Monday to Friday, 9am-5pm (Standard time zone: UTC/GMT +8 hours).

More Details:39235-58-0 SDS

39235-58-0Relevant articles and documents

Synthesis of the impurity F of salbutamol

Song, Shu-Lian,Lian, Cheng-Xi,Chen, Li-Ping,Huang, Long-Liang

, p. 956 - 965 (2020/06/30)

First synthesis of the diastereomeric mixture of salbutamol impurity F is described in seven steps by using 4-hydroxyacetophenone as starting material, with 15.2percent total yield. The synthesis provides access to multi-gram quantities of impurity F with good purity for reference supplies and further analytical and toxicology investigations. (Figure presented.).

5-(1-Acetoxyvinyl)-cyclosaligenyl-2′,3′-dideoxy-2′, 3′- didehydrothymidine monophosphates, a second type of new, enzymatically activated cyclosaligenyl pronucleotides

Gisch, Nicolas,Pertenbreiter, Florian,Balzarini, Jan,Meier, Chris

supporting information; experimental part, p. 8115 - 8123 (2009/12/07)

In our attempt to further develop the cycloSal pronucleotide concept, we report on 5-(1-acetoxyvinyl)-cycloSal-d4TMPs as a new type of enzyme-activated pronucleotides. These compounds were converted into 5-acetyl-cycloSal-d4TMPs by (carboxy)esterase cleav

Synthesis and Insecticidal Activity of Some New 3-Substituted 4-Hydroxyacetophenones

Borthakur, R. C.,Borthakur, N.,Rastogi, R. C.

, p. 244 - 248 (2007/10/02)

A number of 3-(N,N-dialkylaminomethyl)-4-hydroxy acetophenones (4-10) and their thiophosphorylated compounds (11-16) have been synthesised and screened for their insecticidal activity.Only thiophosphorylated compounds are found to possess significant activity.The intramolecular hydrogen bonding in these compounds has also been discussed.

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