Technology Process of (3S,4R)-6-(tert-Butyl-diphenyl-silanyloxy)-3,4-dimethyl-hexanal
There total 9 articles about (3S,4R)-6-(tert-Butyl-diphenyl-silanyloxy)-3,4-dimethyl-hexanal which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
With
oxalyl dichloride; dimethyl sulfoxide;
In
dichloromethane;
at -78 ℃;
DOI:10.1021/ja961230+
- Guidance literature:
-
Multi-step reaction with 7 steps
1: pyridine / dimethylformamide / 23 °C
2: O3, NaOH / methanol; CH2Cl2 / -78 °C
3: LDA / tetrahydrofuran / -78 °C
4: 30percent aq. H2O2 / CH2Cl2 / 0 °C
5: CuI, BF3*Et2O / tetrahydrofuran / -78 - 0 °C
6: LiAlH4 / tetrahydrofuran / 23 °C
7: 79 percent / (COCl)2, DMSO / CH2Cl2 / -78 °C
With
pyridine; sodium hydroxide; copper(l) iodide; lithium aluminium tetrahydride; oxalyl dichloride; boron trifluoride diethyl etherate; dihydrogen peroxide; ozone; dimethyl sulfoxide; lithium diisopropyl amide;
In
tetrahydrofuran; methanol; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/ja961230+
- Guidance literature:
-
Multi-step reaction with 8 steps
1: NaBH4 / methanol / 23 °C
2: pyridine / dimethylformamide / 23 °C
3: O3, NaOH / methanol; CH2Cl2 / -78 °C
4: LDA / tetrahydrofuran / -78 °C
5: 30percent aq. H2O2 / CH2Cl2 / 0 °C
6: CuI, BF3*Et2O / tetrahydrofuran / -78 - 0 °C
7: LiAlH4 / tetrahydrofuran / 23 °C
8: 79 percent / (COCl)2, DMSO / CH2Cl2 / -78 °C
With
pyridine; sodium hydroxide; sodium tetrahydroborate; copper(l) iodide; lithium aluminium tetrahydride; oxalyl dichloride; boron trifluoride diethyl etherate; dihydrogen peroxide; ozone; dimethyl sulfoxide; lithium diisopropyl amide;
In
tetrahydrofuran; methanol; dichloromethane; N,N-dimethyl-formamide;
DOI:10.1021/ja961230+
