(R)-2-[1-(N-benzyloxycarbonylsulfamoyl)pyrrolidin-3-ylamino]-5-cyano-N-(3,4-dimethoxybenzyl)benzamide

Base Information

Chemical Name:(R)-2-[1-(N-benzyloxycarbonylsulfamoyl)pyrrolidin-3-ylamino]-5-cyano-N-(3,4-dimethoxybenzyl)benzamide
CAS No.:247569-20-6
Molecular Formula:C₂₉H₃₁N₅O₇S
Molecular Weight:593.66
Hs Code.:

Synonyms:(R)-2-[1-(N-benzyloxycarbonylsulfamoyl)pyrrolidin-3-ylamino]-5-cyano-N-(3,4-dimethoxybenzyl)benzamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of (R)-2-[1-(N-benzyloxycarbonylsulfamoyl)pyrrolidin-3-ylamino]-5-cyano-N-(3,4-dimethoxybenzyl)benzamide

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Technology Process of (R)-2-[1-(N-benzyloxycarbonylsulfamoyl)pyrrolidin-3-ylamino]-5-cyano-N-(3,4-dimethoxybenzyl)benzamide

There total 2 articles about (R)-2-[1-(N-benzyloxycarbonylsulfamoyl)pyrrolidin-3-ylamino]-5-cyano-N-(3,4-dimethoxybenzyl)benzamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 1189-71-5
isocyanate de chlorosulfonyle

: 247569-14-8
(R)-5-cyano-N-(3,4-dimethoxybenzyl)-2-(3-pyrrolidinylamino)benzamide

: 247569-20-6
(R)-2-[1-(N-benzyloxycarbonylsulfamoyl)pyrrolidin-3-ylamino]-5-cyano-N-(3,4-dimethoxybenzyl)benzamide

Guidance literature:: With triethylamine; benzyl alcohol; In methanol; chloroform; 1,2-dichloro-ethane;

Reference yield:

: 247569-21-7
5-cyano-N-(3,4-dimethoxybenzyl)-2-fluorobenzamide

: 247569-20-6
(R)-2-[1-(N-benzyloxycarbonylsulfamoyl)pyrrolidin-3-ylamino]-5-cyano-N-(3,4-dimethoxybenzyl)benzamide

Guidance literature:: Multi-step reaction with 3 steps

2: trifluoroacetic acid / chloroform

3: triethylamine; benzyl alcohol / methanol; chloroform; 1,2-dichloro-ethane

With triethylamine; trifluoroacetic acid; benzyl alcohol; In methanol; chloroform; 1,2-dichloro-ethane;