3-[19-{2-[bis(4-methoxyphenyl)(phenyl)methoxy]ethoxy}-3,15-dihexadecyl-6,12-dioxa-3,9,15,21-tetraazabicyclo[15.3.1]henicosa-1⁽²¹⁾,17,19-trien-9-yl]propan-1-ol

Base Information

• Chemical Name: 3-[19-{2-[bis(4-methoxyphenyl)(phenyl)methoxy]ethoxy}-3,15-dihexadecyl-6,12-dioxa-3,9,15,21-tetraazabicyclo[15.3.1]henicosa-1⁽²¹⁾,17,19-trien-9-yl]propan-1-ol
• CAS No.: 923578-71-6
• Molecular Formula: C₇₃H₁₁₈N₄O₇
• Molecular Weight: 1163.76
• Mol file: 923578-71-6.mol

Synonyms:3-[19-{2-[bis(4-methoxyphenyl)(phenyl)methoxy]ethoxy}-3,15-dihexadecyl-6,12-dioxa-3,9,15,21-tetraazabicyclo[15.3.1]henicosa-1⁽²¹⁾,17,19-trien-9-yl]propan-1-ol

Chemical Property of 3-[19-{2-[bis(4-methoxyphenyl)(phenyl)methoxy]ethoxy}-3,15-dihexadecyl-6,12-dioxa-3,9,15,21-tetraazabicyclo[15.3.1]henicosa-1⁽²¹⁾,17,19-trien-9-yl]propan-1-ol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 3-[19-{2-[bis(4-methoxyphenyl)(phenyl)methoxy]ethoxy}-3,15-dihexadecyl-6,12-dioxa-3,9,15,21-tetraazabicyclo[15.3.1]henicosa-1⁽²¹⁾,17,19-trien-9-yl]propan-1-ol

There total 2 articles about 3-[19-{2-[bis(4-methoxyphenyl)(phenyl)methoxy]ethoxy}-3,15-dihexadecyl-6,12-dioxa-3,9,15,21-tetraazabicyclo[15.3.1]henicosa-1⁽²¹⁾,17,19-trien-9-yl]propan-1-ol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 41.0%

4-[2-(4,4'-dimethoxytrityl)-oxy-ethoxy]-pyridine-2,6-dicarbaldehyde (923578-70-5) + 3-(bis{2-[2-(hexadecylamino)ethoxy]ethyl}amino)propan-1-ol (923578-79-4) → 3-[19-{2-[bis(4-methoxyphenyl)(phenyl)methoxy]ethoxy}-3,15-dihexadecyl-6,12-dioxa-3,9,15,21-tetraazabicyclo[15.3.1]henicosa-1(21),17,19-trien-9-yl]propan-1-ol (923578-71-6)

Guidance literature:

4-[2-(4,4'-dimethoxytrityl)-oxy-ethoxy]-pyridine-2,6-dicarbaldehyde; 3-(bis{2-[2-(hexadecylamino)ethoxy]ethyl}amino)propan-1-ol; With sodium tris(acetoxy)borohydride; In 1,2-dichloro-ethane; at 20 ℃; for 48h; Molecular sieve 3?;

With sodium hydrogencarbonate; In water; 1,2-dichloro-ethane; for 2h;

Reference yield:

4-[2-(4,4'-dimethoxytrityl)-oxy-ethoxy]-pyridine-2,6-dicarbaldehyde (923578-70-5) + 3-(bis{2-[2-(hexadecylamino)ethoxy]ethyl}amino)propan-1-ol (923578-79-4) + sodium tris(acetoxy)borohydride (56553-60-7) → 3-[19-{2-[bis(4-methoxyphenyl)(phenyl)methoxy]ethoxy}-3,15-dihexadecyl-6,12-dioxa-3,9,15,21-tetraazabicyclo[15.3.1]henicosa-1(21),17,19-trien-9-yl]propan-1-ol (923578-71-6)

Guidance literature:

With sodium hydrogencarbonate; silica gel; In 1,2-dichloro-ethane;

Reference yield: 60.0%

3-[19-{2-[bis(4-methoxyphenyl)(phenyl)methoxy]ethoxy}-3,15-dihexadecyl-6,12-dioxa-3,9,15,21-tetraazabicyclo[15.3.1]henicosa-1(21),17,19-trien-9-yl]propan-1-ol (923578-71-6) + bis(2-cyanoethyl) diisopropylamidophosphite (102690-88-0) → 3-[19-{2-[bis(4-methoxyphenyl)(phenyl)methoxy]ethoxy}-3,15-dihexadecyl-6,12-dioxa-3,9,15,21-tetraazabicyclo[15.3.1]henicosa-1(21),17,19-trien-9-yl]propan-2-cyanoethyldiisopropyl-amidophosphite (923578-82-9)

Guidance literature:

With N-ethyl-N,N-diisopropylamine; In dichloromethane; at 0 ℃; for 1h;

upstream raw materials:

4-[2-(4,4'-dimethoxytrityl)-oxy-ethoxy]-pyridine-2,6-dicarbaldehyde

3-(bis{2-[2-(hexadecylamino)ethoxy]ethyl}amino)propan-1-ol

sodium tris(acetoxy)borohydride

Downstream raw materials:

3-[19-{2-[bis(4-methoxyphenyl)(phenyl)methoxy]ethoxy}-3,15-dihexadecyl-6,12-dioxa-3,9,15,21-tetraazabicyclo[15.3.1]henicosa-1⁽²¹⁾,17,19-trien-9-yl]propan-2-cyanoethyldiisopropyl-amidophosphite