trans-{(PPh₃)2Pd(CNC₆H₄-p-Me)Cl}BF₄

Base Information

• Chemical Name: trans-{(PPh₃)2Pd(CNC₆H₄-p-Me)Cl}BF₄
• CAS No.: 110313-88-7
• Molecular Formula: BF₄*C₄₄H₃₇ClNP₂Pd
• Molecular Weight: 870.41
• Mol file: 110313-88-7.mol

Synonyms:trans-{(PPh₃)2Pd(CNC₆H₄-p-Me)Cl}BF₄

Chemical Property of trans-{(PPh₃)2Pd(CNC₆H₄-p-Me)Cl}BF₄

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

SDS file from LookChem

Useful:

Technology Process of trans-{(PPh₃)2Pd(CNC₆H₄-p-Me)Cl}BF₄

There total 1 articles about trans-{(PPh₃)2Pd(CNC₆H₄-p-Me)Cl}BF₄ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 86.0%

sodium tetrafluoroborate (13755-29-8) + trans-bis(triphenylphosphine)palladium dichloride (28966-81-6) + 4-methylphenyl isocyanide (7175-47-5) → trans-{(PPh3)2Pd(CNC6H4-p-Me)Cl}BF4 (110313-88-7) + sodium chloride (7647-14-5)

Guidance literature:

In acetone; under inert gas; dropwise addn. of the isocyanide in acetone to the suspn. of the Pd complex in acetone in presence of NaBF4 at room temp.; stirring for 1 h; solvent removed, residue dissolved in CH2Cl2; soln. filtered and concd., addn. of Et2O yields the solid; elem. anal.;

Reference yield: 52.0%

sodium tetrafluoroborate (13755-29-8) + n-butyllithium (109-72-8,29786-93-4) + trans-{(PPh3)2Pd(CNC6H4-p-Me)Cl}BF4 (110313-88-7) + 2-bromoethylamine hydrobromide (2576-47-8) → trans-{(PPh3)2Pd(CN(C6H4-p-Me)CH2CH2N(H))Br}BF4 (111139-95-8)

Guidance literature:

In tetrahydrofuran; hexane; under inert gas; suspn. of the ammonium salt in THF treated with n-BuLi at 0°C; addn. of the Pd complex; reaction mixt. allowed to reach room temp.; stirring (45 min); evapn.; residue dissolved in acetone, soln. treated with NaBF4; stirring (3 h); reaction mixt. taken to dryness, residue dissolved in CH2Cl2; filtration, addn. of n-pentane yields the solid product; elem. anal.;

upstream raw materials:

sodium tetrafluoroborate

trans-bis(triphenylphosphine)palladium dichloride

4-methylphenyl isocyanide

Downstream raw materials:

trans-{(PPh₃)2Pd(CN(C₆H₄-p-Me)CH₂CH₂N(H))Br}BF₄

Refernces