Chemical Property of Congo red
Chemical Property:
- Appearance/Colour:brown-red powder
- Vapor Pressure:<1 Pa
- Melting Point:>360 °C(lit.)
- PKA:4.1(at 25℃)
- PSA：232.64000
- Density:0.995 g/mL at 25 °C
- LogP:10.78740
- Storage Temp.:Flammables area
- Solubility.:H2O: soluble10mg/mL
- Water Solubility.:soluble
- Hydrogen Bond Donor Count:2
- Hydrogen Bond Acceptor Count:12
- Rotatable Bond Count:5
- Exact Mass:696.08376335
- Heavy Atom Count:48
- Complexity:1180
- Purity/Quality:
-
99% *data from raw suppliers
Direct Red 28 *data from reagent suppliers
Safty Information:
- Pictogram(s):
T, 
Xi
- Hazard Codes:T,Xi
- Statements:
45-63-36
- Safety Statements:
53-45-37/39-26
- MSDS Files:
-
SDS file from LookChem
Useful:
- Chemical Classes:Dyes -> Benzidine Dyes
- Canonical SMILES:C1=CC=C2C(=C1)C(=CC(=C2N)N=NC3=CC=C(C=C3)C4=CC=C(C=C4)N=NC5=C(C6=CC=CC=C6C(=C5)S(=O)(=O)[O-])N)S(=O)(=O)[O-].[Na+].[Na+]
- Recent NIPH Clinical Trials:Role of cellular senescence in gastric carcinogenesis after eradication of Helicobacter pylori
-
Uses
1. It has been widely used in cotton, viscose dyeing. Because it can easily be transformed into blue when in acid, while there is no appropriate treatment to improve, the usage amount is gradually decreased since the advent of insoluble azo dyes and acid-resistant red 4BS, however, the amount used in the paper industry is quite large. It can also be used as indicators of acid-base, namely Congo red test paper. The measurable range pH is 3.0 (blue)-5.0 (red). It is also used for biological staining, analysis reagents.
2. An indicator frequently used in lab as well as a carcinogenic disperse dyes; used to standard test.
3. Used as an acid-base indicator, adsorption indicator and biological stain, etc.
4. Acid-base indicator, pH 3.0 (blue violet)~5.0 (red); detect the acidity of paper and hydrochloric acid in the gastric juice; test boric acid, cyanide; biological media additives; biological staining, such as embryo slices, plant mucin, cellulose, elastic tissue dyeing.
5. Mainly used for dyeing cotton, hemp, silk and other textile and paper products; it can also be used as an indicator. Dye, medicine (diagnostic aid), indicator, biological stain. Congo red is useful for staining and visual detection of amyloid deposits. It inhibits the accumulation of the scrapie-associated, protease-resistant isoform of protein PrP without affecting the metabolism of the normal isoform. Congo red has been used as a histochemical stain for the quantification of amyloid deposits in brain tissues. It has been used as a cell wall inhibiting agent in fungus Cryptococcus neoformans. It has also been used to study microstructural details in the cell walls of raw potato and fried potato using confocal microscopy.
