N-[(2E)-2-benzylidene-3,4-dihydronaphthalen-1(2H)-ylidene]-4-methylbenzenesulfonamide

Base Information

• Chemical Name: N-[(2E)-2-benzylidene-3,4-dihydronaphthalen-1(2H)-ylidene]-4-methylbenzenesulfonamide
• CAS No.: 1273224-18-2
• Molecular Formula: C₂₄H₂₁NO₂S
• Molecular Weight: 387.502
• Mol file: 1273224-18-2.mol

Synonyms:N-[(2E)-2-benzylidene-3,4-dihydronaphthalen-1(2H)-ylidene]-4-methylbenzenesulfonamide

Chemical Property of N-[(2E)-2-benzylidene-3,4-dihydronaphthalen-1(2H)-ylidene]-4-methylbenzenesulfonamide

Chemical Property:

Purity/Quality:

Safty Information:

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MSDS Files:

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Technology Process of N-[(2E)-2-benzylidene-3,4-dihydronaphthalen-1(2H)-ylidene]-4-methylbenzenesulfonamide

There total 1 articles about N-[(2E)-2-benzylidene-3,4-dihydronaphthalen-1(2H)-ylidene]-4-methylbenzenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 77.0%

(E)-2-benzylidene-1-tetralone (6261-32-1) + toluene-4-sulfonamide (70-55-3) → N-[(2E)-2-benzylidene-3,4-dihydronaphthalen-1(2H)-ylidene]-4-methylbenzenesulfonamide (1273224-18-2)

Guidance literature:

With titanium tetrachloride; triethylamine; In dichloromethane; at 0 ℃; for 18h; Reflux;

DOI:10.1002/ejoc.201701806

Reference yield: 83.0%

N-[(2E)-2-benzylidene-3,4-dihydronaphthalen-1(2H)-ylidene]-4-methylbenzenesulfonamide (1273224-18-2) + ethyl 2-((tert-butoxycarbonyloxy)methyl)acrylate → ethyl trans-2-(3-phenyl-1-tosyl-2,3,4,5-tetrahydro-1H-benzo[g]indol-2-yl)acrylate

Guidance literature:

With triphenylphosphine; In dichloromethane; at 20 ℃; for 24h; optical yield given as %de; diastereoselective reaction; Inert atmosphere;

DOI:10.1021/jo200164v

Reference yield: 81.0%

N-[(2E)-2-benzylidene-3,4-dihydronaphthalen-1(2H)-ylidene]-4-methylbenzenesulfonamide (1273224-18-2) + N-aminophthalamide (1875-48-5) → N-[rel-(2R,3S)-1-(1,3-dioxoisoindol-2-yl)-3-phenyl-3',4'-dihydro-1'H-spiro[aziridine-2,2'-naphthalen]-1'-ylidene]-4-methylbenzenesulfonamide

Guidance literature:

With lead(IV) tetraacetate; potassium carbonate; In dichloromethane; at 0 ℃; for 0.75h;

DOI:10.1002/ejoc.201701806

upstream raw materials:

(E)-2-benzylidene-1-tetralone

toluene-4-sulfonamide