Ethyl 3-acetyl-5-(1,1-dimethylethyl)-2-hydroxybenzoate

Base Information

Chemical Name:Ethyl 3-acetyl-5-(1,1-dimethylethyl)-2-hydroxybenzoate
CAS No.:187273-02-5
Molecular Formula:C₁₅H₂₀O₄
Molecular Weight:264.321
Hs Code.:
DSSTox Substance ID:DTXSID901210477

Synonyms:SCHEMBL6971420;DTXSID901210477;Ethyl 3-acetyl-5-(1,1-dimethylethyl)-2-hydroxybenzoate;187273-02-5

Suppliers and Price of Ethyl 3-acetyl-5-(1,1-dimethylethyl)-2-hydroxybenzoate

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

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Total 0 raw suppliers

Chemical Property of Ethyl 3-acetyl-5-(1,1-dimethylethyl)-2-hydroxybenzoate

Chemical Property:

XLogP3:3.7
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:4
Rotatable Bond Count:5
Exact Mass:264.13615911
Heavy Atom Count:19
Complexity:343

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:CCOC(=O)C1=CC(=CC(=C1O)C(=O)C)C(C)(C)C

Technology Process of Ethyl 3-acetyl-5-(1,1-dimethylethyl)-2-hydroxybenzoate

There total 3 articles about Ethyl 3-acetyl-5-(1,1-dimethylethyl)-2-hydroxybenzoate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 45.0%

: 506-96-7
Acetyl bromide

: 507-20-0
tertiary butyl chloride

: 118-61-6
2-hydroxy-benzoic acid ethyl ester

: 187273-02-5
5-t-butyl-3-ethoxycarbonyl-2-hydroxyacetophenone

Guidance literature:: With hydrogenchloride; aluminium trichloride; In dichloromethane;

Reference yield:

: 118-61-6
2-hydroxy-benzoic acid ethyl ester

: 187273-02-5
5-t-butyl-3-ethoxycarbonyl-2-hydroxyacetophenone

Guidance literature:: Multi-step reaction with 2 steps

1: AlCl₃ / CH₂Cl₂ / 3 h / Ambient temperature

2: AlCl₃ / CH₂Cl₂

With aluminium trichloride; In dichloromethane;
DOI:10.1021/jm960628d