4-fluoro-N-(4-nitrophenyl)benzenesulfonamide

Base Information

Chemical Name:4-fluoro-N-(4-nitrophenyl)benzenesulfonamide
CAS No.:312-60-7
Molecular Formula:C₁₂H₉FN₂O₄S
Molecular Weight:296.279
Hs Code.:
DSSTox Substance ID:DTXSID901256817
Mol file:312-60-7.mol

Synonyms:4-fluoro-N-(4-nitrophenyl)benzenesulfonamide;4-fluoro-N-{4-nitrophenyl}benzenesulfonamide;Cambridge id 5343780;SCHEMBL21247922;DTXSID901256817;STK017179;AKOS000673735;312-60-7;AG-690/11634907

Suppliers and Price of 4-fluoro-N-(4-nitrophenyl)benzenesulfonamide

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of 4-fluoro-N-(4-nitrophenyl)benzenesulfonamide

Chemical Property:

XLogP3:2.9
Hydrogen Bond Donor Count:1
Hydrogen Bond Acceptor Count:6
Rotatable Bond Count:3
Exact Mass:296.02670611
Heavy Atom Count:20
Complexity:429

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:C1=CC(=CC=C1NS(=O)(=O)C2=CC=C(C=C2)F)[N+](=O)[O-]

Technology Process of 4-fluoro-N-(4-nitrophenyl)benzenesulfonamide

There total 1 articles about 4-fluoro-N-(4-nitrophenyl)benzenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 98.0%

: 349-88-2
4-Fluorobenzenesulfonyl chloride

: 100-01-6,104810-17-5
4-nitro-aniline

: 312-60-7
4-fluoro-N-(4-nitrophenyl)benzenesulfonamide

Guidance literature:: With pyridine; In dichloromethane; at 20 ℃; for 24h; Cooling with ice;

Reference yield: 80.0%

: 312-60-7
4-fluoro-N-(4-nitrophenyl)benzenesulfonamide

: 793727-98-7
N-(4-aminophenyl)-4-fluorobenzenesulfonamide

Guidance literature:: With palladium on carbon; hydrogen; In methanol; ethyl acetate; at 20 ℃; for 24h;

Reference yield:

: 312-60-7
4-fluoro-N-(4-nitrophenyl)benzenesulfonamide

: N-(4-((4-fluorophenyl)sulfonamido)phenyl)-5-nitrofuran-2-carboxamide

Guidance literature:: Multi-step reaction with 2 steps

1.1: iron; ammonium chloride / water; ethanol / 55 - 90 °C

2.1: triethylamine; HATU; pyridine / N,N-dimethyl-formamide / 0.25 h / 20 °C

2.2: 20 °C

With pyridine; iron; ammonium chloride; triethylamine; HATU; In ethanol; water; N,N-dimethyl-formamide;
DOI:10.1016/j.ejmech.2021.113859