Technology Process of 2-benzyl-3,3-ethylenedioxybutanal
There total 7 articles about 2-benzyl-3,3-ethylenedioxybutanal which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
pyridine; chromium(VI) oxide;
In
dichloromethane;
at 20 ℃;
for 2.5h;
- Guidance literature:
-
Multi-step reaction with 4 steps
1.1: sodium hydride / toluene; N,N-dimethyl-formamide; mineral oil / 8 h / 20 - 100 °C
2.1: toluene-4-sulfonic acid / toluene / 18 h / Reflux; Dean-Stark
3.1: lithium aluminium tetrahydride / tetrahydrofuran / 2 h / 20 °C
4.1: oxalyl dichloride; dimethyl sulfoxide / dichloromethane / 0.5 h / -78 °C
4.2: 1 h / -78 - 20 °C
With
lithium aluminium tetrahydride; oxalyl dichloride; sodium hydride; toluene-4-sulfonic acid; dimethyl sulfoxide;
In
tetrahydrofuran; dichloromethane; N,N-dimethyl-formamide; toluene; mineral oil;
DOI:10.1021/acs.orglett.6b00151
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: toluene-4-sulfonic acid / toluene / 18 h / Reflux; Dean-Stark
2.1: lithium aluminium tetrahydride / tetrahydrofuran / 2 h / 20 °C
3.1: oxalyl dichloride; dimethyl sulfoxide / dichloromethane / 0.5 h / -78 °C
3.2: 1 h / -78 - 20 °C
With
lithium aluminium tetrahydride; oxalyl dichloride; toluene-4-sulfonic acid; dimethyl sulfoxide;
In
tetrahydrofuran; dichloromethane; toluene;
DOI:10.1021/acs.orglett.6b00151
