1-methyl-1H-indole-3-carboxylic acid phenylamide

Base Information

Chemical Name:1-methyl-1H-indole-3-carboxylic acid phenylamide
CAS No.:82414-31-1
Molecular Formula:C₁₆H₁₄N₂O
Molecular Weight:250.3
Hs Code.:

Synonyms:1-methyl-1H-indole-3-carboxylic acid phenylamide

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Chemical Property of 1-methyl-1H-indole-3-carboxylic acid phenylamide

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Technology Process of 1-methyl-1H-indole-3-carboxylic acid phenylamide

There total 12 articles about 1-methyl-1H-indole-3-carboxylic acid phenylamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 88.0%

: 103-72-0
phenyl isothiocyanate

: 16136-58-6
N-methyl-1H-indole-2-carboxylic acid

: 82414-31-1
1-methyl-1H-indole-3-carboxylic acid phenylamide

Guidance literature:: With tetrabutylammomium bromide; palladium diacetate; caesium carbonate; In acetonitrile; at 80 ℃; for 6h;
DOI:10.1021/acs.joc.8b00042

Reference yield: 85.0%

: 66003-76-7
Diphenyliodonium triflate

: 24662-37-1
1-methyl-1H-indole-3-carbonitrile

: 82414-31-1
1-methyl-1H-indole-3-carboxylic acid phenylamide

Guidance literature:: With copper(II) bis(trifluoromethanesulfonate); In water; 1,2-dichloro-ethane; at 80 ℃; for 12h; chemoselective reaction; Inert atmosphere;
DOI:10.1039/d0ob02247k

Reference yield: 68.0%

: 32387-21-6
1-methyl-3-indolecarboxylic acid

: 62-53-3
aniline

: 82414-31-1
1-methyl-1H-indole-3-carboxylic acid phenylamide

Guidance literature:: With PS-carbodiimide; benzotriazol-1-ol; In 1-methyl-pyrrolidin-2-one; at 100 ℃; for 0.0833333h; microwave irradiation;
DOI:10.1021/ol0358915