1,2-(E,E)-distyrylcyclohexene

Base Information

• Chemical Name: 1,2-(E,E)-distyrylcyclohexene
• CAS No.: 30984-01-1
• Molecular Formula: C₂₂H₂₂
• Molecular Weight: 286.417
• Mol file: 30984-01-1.mol

Synonyms:1,2-(E,E)-distyrylcyclohexene

Chemical Property of 1,2-(E,E)-distyrylcyclohexene

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,2-(E,E)-distyrylcyclohexene

There total 8 articles about 1,2-(E,E)-distyrylcyclohexene which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 69.0%

styrene (100-42-5,25038-60-2,25247-68-1,28213-80-1,28325-75-9,79637-11-9,9003-53-6) + 1,2-dibromocyclohex-1-ene (49676-92-8) → 1,2-(E,E)-distyrylcyclohexene (30984-01-1)

Guidance literature:

With palladium diacetate; triethylamine; triphenylphosphine; In N,N-dimethyl-formamide; at 90 ℃; for 92h;

DOI:10.1002/(SICI)1099-0690(199808)1998:8<1521::AID-EJOC1521>3.0.CO;2-E

Reference yield: 33.0%

styrene (100-42-5,25038-60-2,25247-68-1,28213-80-1,28325-75-9,79637-11-9,9003-53-6) + 1-bromo-2-trifluoromethanesulfonyloxycyclohexene (213340-08-0) → 1,2-(E,E)-distyrylcyclohexene (30984-01-1)

Guidance literature:

With palladium diacetate; triethylamine; triphenylphosphine; lithium chloride; In N,N-dimethyl-formamide; at 90 ℃; for 96h;

DOI:10.1002/(SICI)1099-0690(199808)1998:8<1521::AID-EJOC1521>3.0.CO;2-E

Reference yield:

2-(phenylacetylenyl)cyclohex-1-enecarbaldehyde (21403-38-3) → 1,2-(E,E)-distyrylcyclohexene (30984-01-1)

Guidance literature:

Multi-step reaction with 3 steps

1: H₂ / Pd-C / ethyl acetate

2: 2,2,4-trimethyl-pentane / Heating

3: (i) KOtBu, (ii) /BRN= 2047965/, Et₂O

With hydrogen; palladium on activated charcoal; In 2,2,4-trimethylpentane; ethyl acetate;

DOI:10.1002/hlca.19700530720

upstream raw materials:

2-(trans-β-styryl)-3,4,5,6-tetrahydrobenzaldehyde

benzyltriphenylphosphonium chloride

styrene

1,2-dibromocyclohex-1-ene

Downstream raw materials:

cis-2,3-Diphenyl-2,3,5,6,7,8-hexahydro-naphthalin