49676-92-8

Basic information

• Product Name: 1,2-dibromocyclohexene
• Synonyms: 1,2-Dibromocyclohexene; cyclohexene, 1,2-dibromo-
• CAS NO: 49676-92-8
• Molecular Formula: C₆H₈Br₂
• Molecular Weight: 239.9357
• Mol File: 49676-92-8.mol
• Article Data: 5

Chemical Properties

• Boiling Point: 226.4°C at 760 mmHg
• Flash Point: 96.3°C
• Density: 1.927g/cm³
• Vapor Pressure: 0.123mmHg at 25°C
• Refractive Index: 1.604
• CAS DataBase Reference: 1,2-dibromocyclohexene(CAS DataBase Reference)
• NIST Chemistry Reference: 1,2-dibromocyclohexene(49676-92-8)
• EPA Substance Registry System: 1,2-dibromocyclohexene(49676-92-8)

Safety Data

• Hazardous Substances Data: 49676-92-8(Hazardous Substances Data)

Usage

Physical state

Colorless liquid

Molecular weight

235.94 g/mol

Uses

a. Organic synthesis
b. Intermediate in manufacturing pharmaceuticals and chemical products

Reactivity

Highly reactive due to the presence of two bromine atoms

Applications

a. Introducing bromine atoms into organic molecules
b. Precursor in the production of flame retardants and polymers
c. Potential applications in medicine, specifically in the development of anticancer drugs and other pharmaceuticals

Safety

Toxic and should be handled with care in a controlled laboratory environment

Upstream product

• 98139-95-8 1,2-dibromo-1-chlorocyclohexane 
• 108-94-1 cyclohexanone 
• 930-66-5 1-chlorocyclohexene 

Downstream Products

• 224316-65-8 (E)-3-(2-{(E)-2-[(1R,2S,5R)-5-Methyl-2-(1-methyl-1-phenyl-ethyl)-cyclohexyloxycarbonyl]-vinyl}-cyclohex-1-enyl)-acrylic acid (1R,2S,5R)-5-methyl-2-(1-methyl-1-phenyl-ethyl)-cyclohexyl ester 
• 114493-71-9 1,2-diiodocyclohex-1-ene 
• 124-04-9 Adipic acid 
• 20696-89-3 cyclohexene-d₂^1,2 
• 180515-43-9 (1R,2S,3S)-1-[Benzyl-((S)-1-phenyl-ethyl)-amino]-3-tert-butoxycarbonylmethyl-2,3,4,5,6,7-hexahydro-1H-indene-2-carboxylic acid tert-butyl ester 

Relevant articles and documents

Cyclohexeno[3,4]cyclodec-1,5-diyne-3-ene: A Convenient Enediyne

Enediynes are widely studied to understand their cycloaromatization and the trapping of the resulting p-dehydrobenzene diradical. However, few model substrates are known, and they are hard to synthesize and difficult to handle. Herein we report cyclohexen

Synthesis of Fulvene Vinyl Ethers by Gold Catalysis

Gold-catalyzed cyclization of 1,5-diynes with ketones as reagents and solvent provides diversely substituted vinyl ethers under mild conditions. The regioselectivity of such gold-catalyzed cyclizations is usually controlled by the scaffold of the diyne. H

Auto-tandem catalysis: Synthesis of acridines by Pd-catalyzed C=C bond formation and C(sp2)-N cross-coupling

A facile palladium-catalyzed synthesis of acridines has been realized by consecutive C=C double bond formation and C-N cross-coupling. A variety of functionalized acridines can be accessed from easily available o-dihalobenzenes and N-tosylhydrazones in a single operation. This one-pot protocol has a wide scope with respect to both coupling partners, and provides an efficient route to functionalized acridine derivatives, which are generally difficult to synthesize by previously known methods.