49676-92-8

Usage

Physical state

Colorless liquid

Molecular weight

235.94 g/mol

Uses

a. Organic synthesis
b. Intermediate in manufacturing pharmaceuticals and chemical products

Reactivity

Highly reactive due to the presence of two bromine atoms

Applications

a. Introducing bromine atoms into organic molecules
b. Precursor in the production of flame retardants and polymers
c. Potential applications in medicine, specifically in the development of anticancer drugs and other pharmaceuticals

Safety

Toxic and should be handled with care in a controlled laboratory environment

Upstream product

• 98139-95-8 1,2-dibromo-1-chlorocyclohexane 
• 930-66-5 1-chlorocyclohexene 
• 108-94-1 cyclohexanone 

Downstream Products

• 54526-84-0 (E)-3-(cyclohex-1-ene)-prop-2-enoic acid methyl ester 
• 131496-56-5 methyl (E)-3-{2-[(E)-2-(methoxycarbonyl)ethenyl]-1-cyclohexen-1-yl}acrylate 
• 30984-01-1 1,2-(E,E)-distyrylcyclohexene 
• 124-04-9 Adipic acid 
• 108-86-1 bromobenzene 
• 583-53-9 2,3-dibromobenzene 
• 91-20-3 naphthalene 
• 42429-92-5 7,8,9,10-tetrahydrofluoranthene 
• 20696-89-3 cyclohexene-d₂^1,2 
• 139989-04-1 cyclohexynebis(di-t-butylphenylphosphine)platinum⁽⁰⁾ 
• 42764-88-5 trans-chlorohydridobis(tricyclohexylphosphine)platinum(II) 
• 139965-60-9 cyclohexynebis(t-butyldiphenylphosphine)platinum⁽⁰⁾ 
• 1610-39-5 1,2,3,4,5,6,7,8,9,10,11,12-dodecahydrotriphenylene 
• 114493-71-9 1,2-diiodocyclohex-1-ene 

Relevant academic research and scientific papers

Cyclohexeno[3,4]cyclodec-1,5-diyne-3-ene: A Convenient Enediyne

Enediynes are widely studied to understand their cycloaromatization and the trapping of the resulting p-dehydrobenzene diradical. However, few model substrates are known, and they are hard to synthesize and difficult to handle. Herein we report cyclohexen

AROMATIC HETEROCYCLIC SUBSTITUTED OLEFIN COMPOUND, PREPARATION METHOD FOR SAME, PHARMACEUTICAL COMPOSITION OF SAME, AND APPLICATIONS THEREOF

Provided in the present application are an aromatic heterocyclic substituted olefin compound, a preparation method for same, a pharmaceutical composition of same, and applications thereof. The aromatic heterocyclic substituted olefin compound of the present invention is a novel ALK5 inhibitor and is for use in treating and/or preventing various ALK5-mediated diseases.

Synthesis of Fulvene Vinyl Ethers by Gold Catalysis

Gold-catalyzed cyclization of 1,5-diynes with ketones as reagents and solvent provides diversely substituted vinyl ethers under mild conditions. The regioselectivity of such gold-catalyzed cyclizations is usually controlled by the scaffold of the diyne. H

FATTY ACID COMPOUND, PREPARATION METHOD THEREFOR AND USE THEREFOR

The present invention relates to a class of fatty acid compounds, a preparation method thereof and use thereof. The fatty acid compounds have the structure of the formula I, which has the ability to activate APMK and inhibit the glucose output in mouse primary hepatocytes. The fatty acid compounds can be used in preparing a medicament for the treatment of obesity or diabetes.

Auto-tandem catalysis: Synthesis of acridines by Pd-catalyzed C=C bond formation and C(sp2)-N cross-coupling

A facile palladium-catalyzed synthesis of acridines has been realized by consecutive C=C double bond formation and C-N cross-coupling. A variety of functionalized acridines can be accessed from easily available o-dihalobenzenes and N-tosylhydrazones in a single operation. This one-pot protocol has a wide scope with respect to both coupling partners, and provides an efficient route to functionalized acridine derivatives, which are generally difficult to synthesize by previously known methods.