5-cyano-N-[2-(4-isopropyl-2-methanesulfonylaminophenyl)-ethyl]-2-methoxybenzenesulfonamide

Base Information

Chemical Name:5-cyano-N-[2-(4-isopropyl-2-methanesulfonylaminophenyl)-ethyl]-2-methoxybenzenesulfonamide
CAS No.:500303-74-2
Molecular Formula:C₂₀H₂₅N₃O₅S₂
Molecular Weight:451.568
Hs Code.:

Synonyms:5-cyano-N-[2-(4-isopropyl-2-methanesulfonylaminophenyl)-ethyl]-2-methoxybenzenesulfonamide

Suppliers and Price of 5-cyano-N-[2-(4-isopropyl-2-methanesulfonylaminophenyl)-ethyl]-2-methoxybenzenesulfonamide

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 5-cyano-N-[2-(4-isopropyl-2-methanesulfonylaminophenyl)-ethyl]-2-methoxybenzenesulfonamide

Chemical Property:

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Technology Process of 5-cyano-N-[2-(4-isopropyl-2-methanesulfonylaminophenyl)-ethyl]-2-methoxybenzenesulfonamide

There total 3 articles about 5-cyano-N-[2-(4-isopropyl-2-methanesulfonylaminophenyl)-ethyl]-2-methoxybenzenesulfonamide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 409359-25-7
5-cyano-2-methoxybenzenesulfonyl chloride

: 500303-60-6
tert-butyl [2-(4-isopropyl-2-methanesulfonylaminophenyl)-ethyl]carbamate

: 500303-74-2
5-cyano-N-[2-(4-isopropyl-2-methanesulfonylaminophenyl)-ethyl]-2-methoxybenzenesulfonamide

Guidance literature:: With hydrogenchloride; potassium carbonate; In ethanol; at 20 ℃; for 36h; 21% solution of HCl-ethanol;

Reference yield:

: 81592-99-6
5-carbamoyl-2-methoxybenzenesulfonyl chloride

: 500303-74-2
5-cyano-N-[2-(4-isopropyl-2-methanesulfonylaminophenyl)-ethyl]-2-methoxybenzenesulfonamide

Guidance literature:: Multi-step reaction with 2 steps

1: DMF (N,N-dimethyl-formamide) / 3 h / 55 °C

2: hydrogenchloride; potassium carbonate / ethanol / 36 h / 20 °C / 21percent solution of HCl-ethanol

With hydrogenchloride; potassium carbonate; In DMF (N,N-dimethyl-formamide); ethanol;

Reference yield:

: 3424-93-9
4-methoxyphenylacetamide

: 500303-74-2
5-cyano-N-[2-(4-isopropyl-2-methanesulfonylaminophenyl)-ethyl]-2-methoxybenzenesulfonamide

Guidance literature:: Multi-step reaction with 3 steps

1: chlorosulfonic acid / 15.5 h / 20 - 50 °C

2: DMF (N,N-dimethyl-formamide) / 3 h / 55 °C

3: hydrogenchloride; potassium carbonate / ethanol / 36 h / 20 °C / 21percent solution of HCl-ethanol

With hydrogenchloride; chlorosulfonic acid; potassium carbonate; In DMF (N,N-dimethyl-formamide); ethanol;