C₁₁H₈F₄O₂

Base Information

• Chemical Name: C₁₁H₈F₄O₂
• CAS No.: 1333327-24-4
• Molecular Formula: C₁₁H₈F₄O₂
• Molecular Weight: 248.177
• Mol file: 1333327-24-4.mol

Synonyms:C₁₁H₈F₄O₂

Chemical Property of C₁₁H₈F₄O₂

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of C₁₁H₈F₄O₂

There total 1 articles about C₁₁H₈F₄O₂ which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 42.0%

Methyltriphenylphosphonium bromide (1779-49-3) + 1,2,4,5-tetrafluoro-3-(1,3-dioxol-2-yl)-6-formylbenzene (528869-11-6) → C11H8F4O2 (1333327-24-4)

Guidance literature:

Methyltriphenylphosphonium bromide; With n-butyllithium; In diethyl ether; at -20 - 0 ℃; Inert atmosphere;

1,2,4,5-tetrafluoro-3-(1,3-dioxol-2-yl)-6-formylbenzene; In diethyl ether; at 20 ℃; Inert atmosphere;

DOI:10.1016/j.jfluchem.2011.07.021

Reference yield: 81.0%

C11H8F4O2 (1333327-24-4) → C9H4F4O (1333327-25-5)

Guidance literature:

With hydrogenchloride; trifluoroacetic acid; In water; at 60 ℃; for 3h;

DOI:10.1016/j.jfluchem.2011.07.021

Reference yield:

C11H8F4O2 (1333327-24-4) → 4-vinyl-2,3,5,6-tetrafluorobenzylalcohol (139183-76-9)

Guidance literature:

Multi-step reaction with 2 steps

1: hydrogenchloride; trifluoroacetic acid / water / 3 h / 60 °C

2: sodium tetrahydroborate / methanol / 20 °C / Cooling with ice

With hydrogenchloride; sodium tetrahydroborate; trifluoroacetic acid; In methanol; water;

DOI:10.1016/j.jfluchem.2011.07.021

upstream raw materials:

Methyltriphenylphosphonium bromide

1,2,4,5-tetrafluoro-3-(1,3-dioxol-2-yl)-6-formylbenzene

Downstream raw materials:

C₂₁H₁₆F₄O₄

C₂₅H₂₀F₈O₄

C₂₅H₂₄F₄O₄

C₉H₄F₄O