Technology Process of 3-fluoro-4-isopropoxybenzene-1-sulfonyl chloride
There total 3 articles about 3-fluoro-4-isopropoxybenzene-1-sulfonyl chloride which
guide to synthetic route it.
The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:
synthetic route:
- Guidance literature:
-
3-fluoro-4-isopropoxyaniline;
With
hydrogenchloride; acetic acid; sodium nitrite;
In
water;
at -15 ℃;
for 0.5h;
With
sulfur dioxide; acetic acid; copper(l) chloride;
In
water;
at -15 ℃;
for 0.5h;
- Guidance literature:
-
Multi-step reaction with 2 steps
1.1: hydrogen; palladium 10% on activated carbon / methanol / 1 h / 1810.07 Torr
2.1: hydrogenchloride; sodium nitrite; acetic acid / water / 0.5 h / -15 °C
2.2: 0.5 h / -15 °C
With
hydrogenchloride; palladium 10% on activated carbon; hydrogen; acetic acid; sodium nitrite;
In
methanol; water;
- Guidance literature:
-
Multi-step reaction with 3 steps
1.1: potassium carbonate / N,N-dimethyl-formamide / 0.08 h / 20 °C
1.2: 8 h / 20 - 45 °C
2.1: hydrogen; palladium 10% on activated carbon / methanol / 1 h / 1810.07 Torr
3.1: hydrogenchloride; sodium nitrite; acetic acid / water / 0.5 h / -15 °C
3.2: 0.5 h / -15 °C
With
hydrogenchloride; palladium 10% on activated carbon; hydrogen; potassium carbonate; acetic acid; sodium nitrite;
In
methanol; water; N,N-dimethyl-formamide;
