6-benzyloxy-7-methoxy-2-(2-methoxybenzyl)-1,2,3,4-tetrahydroisoquinoline

Base Information

Chemical Name:6-benzyloxy-7-methoxy-2-(2-methoxybenzyl)-1,2,3,4-tetrahydroisoquinoline
CAS No.:1064197-79-0
Molecular Formula:C₂₅H₂₇NO₃
Molecular Weight:389.494
Hs Code.:

Synonyms:6-benzyloxy-7-methoxy-2-(2-methoxybenzyl)-1,2,3,4-tetrahydroisoquinoline

Suppliers and Price of 6-benzyloxy-7-methoxy-2-(2-methoxybenzyl)-1,2,3,4-tetrahydroisoquinoline

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Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 6-benzyloxy-7-methoxy-2-(2-methoxybenzyl)-1,2,3,4-tetrahydroisoquinoline

Chemical Property:

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Technology Process of 6-benzyloxy-7-methoxy-2-(2-methoxybenzyl)-1,2,3,4-tetrahydroisoquinoline

There total 12 articles about 6-benzyloxy-7-methoxy-2-(2-methoxybenzyl)-1,2,3,4-tetrahydroisoquinoline which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

: 98809-69-9
6-(Benzyloxy)-7-methoxy-1,2,3,4-tetrahydroisoquinoline

: 7035-02-1
o-Methoxybenzyl chloride

: 1064197-79-0
6-benzyloxy-7-methoxy-2-(2-methoxybenzyl)-1,2,3,4-tetrahydroisoquinoline

Guidance literature:: With triethylamine; In ethanol; at 120 ℃; for 1h; Microwave irradiation;
DOI:10.1002/cmdc.201300261

Reference yield: 63.0%

: 1064197-79-0
6-benzyloxy-7-methoxy-2-(2-methoxybenzyl)-1,2,3,4-tetrahydroisoquinoline

Guidance literature:

Reference yield:

: 55161-43-8
N-{2-[3-(benzyloxy)-4-methoxyphenyl]ethyl}acetamide

: 1064197-79-0
6-benzyloxy-7-methoxy-2-(2-methoxybenzyl)-1,2,3,4-tetrahydroisoquinoline

Guidance literature:: Multi-step reaction with 3 steps

1: toluene-4-sulfonic acid / toluene / 120 °C

2: water; potassium hydroxide / ethanol / Reflux

3: triethylamine / ethanol / 130 °C / Microwave irradiation

With water; toluene-4-sulfonic acid; triethylamine; potassium hydroxide; In ethanol; toluene;
DOI:10.1021/ml200232c