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2-Methoxybenzyl chloride

Base Information Edit
  • Chemical Name:2-Methoxybenzyl chloride
  • CAS No.:7035-02-1
  • Molecular Formula:C8H9 Cl O
  • Molecular Weight:156.612
  • Hs Code.:2909309090
  • European Community (EC) Number:230-312-4
  • DSSTox Substance ID:DTXSID80220628
  • Nikkaji Number:J227.344F
  • Wikidata:Q72489263
  • Mol file:7035-02-1.mol
2-Methoxybenzyl chloride

Synonyms:2-Methoxybenzyl chloride;7035-02-1;1-(Chloromethyl)-2-methoxybenzene;2-methoxybenzylchloride;2-(Chloromethyl)anisole;1-(Chloromethyl)-2-methoxy-benzene;Benzene, 1-(chloromethyl)-2-methoxy-;MFCD00060276;o-anisyl chloride;Chloromethylanisole;2-methoxybenzyl chlorid;o-Methoxybenzyl chloride;2-methoxy-benzyl chloride;ortho-methoxybenzylchloride;2-methoxyphenylmethyl chloride;SCHEMBL105847;1-chloromethyl-2-methoxybenzene;1-chloromethyl-2-methoxy-benzene;DTXSID80220628;EINECS 230-312-4;CL8709;STL145785;1-(Chloromethyl)-2-methoxybenzene #;AKOS000262078;1-(chloromethyl)-2-(methyloxy)benzene;AC-9750;AM84237;SY018869;FT-0648230;EN300-19045;A24190;W-104558;F0001-1820

Suppliers and Price of 2-Methoxybenzyl chloride
Supply Marketing:Edit
Business phase:
The product has achieved commercial mass production*data from LookChem market partment
Manufacturers and distributors:
  • Manufacture/Brand
  • Chemicals and raw materials
  • Packaging
  • price
  • TRC
  • 1-(Chloromethyl)-2-methoxy-benzene
  • 1g
  • $ 195.00
  • SynQuest Laboratories
  • 2-Methoxybenzyl chloride (50% by weight in Methylene chloride) 99%
  • 10 g
  • $ 59.00
  • SynQuest Laboratories
  • 2-Methoxybenzyl chloride (50% by weight in Methylene chloride) 99%
  • 50 g
  • $ 216.00
  • Matrix Scientific
  • 2-Methoxybenzyl chloride 97%
  • 50g
  • $ 215.00
  • American Custom Chemicals Corporation
  • 2-METHOXYBENZYL CHLORIDE 95.00%
  • 5G
  • $ 1082.56
  • American Custom Chemicals Corporation
  • 2-METHOXYBENZYL CHLORIDE 95.00%
  • 2.5G
  • $ 906.27
  • AK Scientific
  • 2-Methoxybenzylchloride
  • 5g
  • $ 447.00
  • AK Scientific
  • 2-Methoxybenzylchloride
  • 1g
  • $ 147.00
Total 37 raw suppliers
Chemical Property of 2-Methoxybenzyl chloride Edit
Chemical Property:
  • Appearance/Colour:Clear colorless to yellow liquid 
  • Vapor Pressure:0.219mmHg at 25°C 
  • Melting Point:28-30 ºC 
  • Refractive Index:n20/D 1.549(lit.) 
  • Boiling Point:122-124 ºC (26 mmHg) 
  • Flash Point:98 ºC 
  • PSA:9.23000 
  • Density:1.125 
  • LogP:2.43400 
  • Storage Temp.:Refrigerator (+4°C) 
  • XLogP3:2.4
  • Hydrogen Bond Donor Count:0
  • Hydrogen Bond Acceptor Count:1
  • Rotatable Bond Count:2
  • Exact Mass:156.0341926
  • Heavy Atom Count:10
  • Complexity:95.3
Purity/Quality:

98%,99%, *data from raw suppliers

1-(Chloromethyl)-2-methoxy-benzene *data from reagent suppliers

Safty Information:
  • Pictogram(s):  
  • Hazard Codes:
  • Statements: 34 
  • Safety Statements: 26-27-36-45-36/37/39 
MSDS Files:

SDS file from LookChem

Useful:
  • Canonical SMILES:COC1=CC=CC=C1CCl
  • Uses 1-(Chloromethyl)-2-methoxy-benzene is used in the synthesis of indole derivatives in the preparation of anti-cancer agents. Also used to synthesize potent and selective antagonists for the receptor CX3XR1 involved in the treatment of multiple sclerosis.
Technology Process of 2-Methoxybenzyl chloride

There total 26 articles about 2-Methoxybenzyl chloride which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:
Guidance literature:
With triethylamine; In dichloromethane; at 0 - 20 ℃; for 6h; Inert atmosphere;
DOI:10.1016/j.bmc.2021.116513
Guidance literature:
With hydrogenchloride; at 60 ℃; for 10h;
DOI:10.1016/j.ejmech.2019.05.014
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