methyl 3-O-benzyl-4,6-O-benzylidene-2-O-(p-nitrobenzenesulfonyl)-β-D-mannopyranoside

Base Information

• Chemical Name: methyl 3-O-benzyl-4,6-O-benzylidene-2-O-(p-nitrobenzenesulfonyl)-β-D-mannopyranoside
• CAS No.: 1365626-24-9
• Molecular Formula: C₂₇H₂₇NO₁₀S
• Molecular Weight: 557.578
• Mol file: 1365626-24-9.mol

Synonyms:methyl 3-O-benzyl-4,6-O-benzylidene-2-O-(p-nitrobenzenesulfonyl)-β-D-mannopyranoside

Chemical Property of methyl 3-O-benzyl-4,6-O-benzylidene-2-O-(p-nitrobenzenesulfonyl)-β-D-mannopyranoside

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of methyl 3-O-benzyl-4,6-O-benzylidene-2-O-(p-nitrobenzenesulfonyl)-β-D-mannopyranoside

There total 1 articles about methyl 3-O-benzyl-4,6-O-benzylidene-2-O-(p-nitrobenzenesulfonyl)-β-D-mannopyranoside which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 96.0%

methyl 3-O-benzyl-4,6-O-benzylidene-β-D-mannopyranoside (86363-44-2) + 4-Nitrobenzenesulfonyl chloride (98-74-8) → methyl 3-O-benzyl-4,6-O-benzylidene-2-O-(p-nitrobenzenesulfonyl)-β-D-mannopyranoside (1365626-24-9)

Guidance literature:

With pyridine; at 80 ℃; for 24h;

DOI:10.1080/00397911.2010.535950

Reference yield: 98.0%

methyl 3-O-benzyl-4,6-O-benzylidene-2-O-(p-nitrobenzenesulfonyl)-β-D-mannopyranoside (1365626-24-9) → methyl 3-O-benzyl-4,6-O-benzylidene-2-O-(p-aminobenzenesulfonyl)-β-D-mannopyranoside (1365626-27-2)

Guidance literature:

With palladium on activated charcoal; hydrogen; In ethanol; at 20 ℃; for 2h;

DOI:10.1080/00397911.2010.535950

Reference yield:

methyl 3-O-benzyl-4,6-O-benzylidene-2-O-(p-nitrobenzenesulfonyl)-β-D-mannopyranoside (1365626-24-9) → methyl 3-O-benzyl-4,6-O-benzylidene-2-O-(p-(6-carboxy-6-oxohexanoylamino)benzenesulfonyl)-β-D-mannopyranoside (1365626-33-0)

Guidance literature:

Multi-step reaction with 3 steps

1: palladium on activated charcoal; hydrogen / ethanol / 2 h / 20 °C

2: diethylphosphoryl cyanide; triethylamine / dichloromethane / 21 h / 20 °C

3: sodium hydroxide / methanol; water / 2 h / 20 °C

With diethylphosphoryl cyanide; palladium on activated charcoal; hydrogen; triethylamine; sodium hydroxide; In methanol; ethanol; dichloromethane; water;

DOI:10.1080/00397911.2010.535950

upstream raw materials:

methyl 3-O-benzyl-4,6-O-benzylidene-β-D-mannopyranoside

4-Nitrobenzenesulfonyl chloride

Downstream raw materials:

methyl 3-O-benzyl-4,6-O-benzylidene-2-O-(p-aminobenzenesulfonyl)-β-D-mannopyranoside

methyl 3-O-benzyl-4,6-O-benzylidene-2-O-(p-(6-carboxy-6-oxohexanoylamino)benzenesulfonyl)-β-D-mannopyranoside