8-Methoxy-6,7-methylenedioxycoumarin

Base Information

Chemical Name:8-Methoxy-6,7-methylenedioxycoumarin
CAS No.:81558-03-4
Molecular Formula:C₁₁H₈O₅
Molecular Weight:220.182
Hs Code.:
ChEMBL ID:CHEMBL596030
DSSTox Substance ID:DTXSID401227750
Metabolomics Workbench ID:48688
Nikkaji Number:J620.881I
Wikidata:Q105006740

Synonyms:8-Methoxy-6,7-methylenedioxycoumarin;6,7-methylenedioxy-8-methoxycoumarin;81558-03-4;CHEMBL596030;CHEBI:178385;DTXSID401227750;4-methoxy-[1,3]dioxolo[4,5-g]chromen-6-one;4-methoxy-2H,6H-[1,3]dioxolo[4,5-g]chromen-6-one;4-Methoxy-6H-1,3-dioxolo[4,5-g][1]benzopyran-6-one

Suppliers and Price of 8-Methoxy-6,7-methylenedioxycoumarin

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

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Chemical Property of 8-Methoxy-6,7-methylenedioxycoumarin

Chemical Property:

XLogP3:1.7
Hydrogen Bond Donor Count:0
Hydrogen Bond Acceptor Count:5
Rotatable Bond Count:1
Exact Mass:220.03717335
Heavy Atom Count:16
Complexity:326

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Canonical SMILES:COC1=C2C(=CC3=C1OCO3)C=CC(=O)O2

Technology Process of 8-Methoxy-6,7-methylenedioxycoumarin

There total 2 articles about 8-Methoxy-6,7-methylenedioxycoumarin which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

: 4720-68-7
4,5-methylenedioxy-2-hydroxybenzaldehyde

: 81558-03-4
8-methoxy-6,7-methylenedioxycoumarin

Guidance literature:: Multi-step reaction with 3 steps

1: 93 percent / bromine; aluminium(III) chloride / CH₂Cl₂ / 32 h / 20 °C

2: 18 percent / copper(II) chloride / methanol; dimethylformamide / 32 h / 100 °C

3: 77 percent / N,N-diethylaniline / 4 h / 220 °C

With aluminium trichloride; bromine; N,N-diethylaniline; copper dichloride; In methanol; dichloromethane; N,N-dimethyl-formamide; 3: Wittig reaction;
DOI:10.1016/j.tet.2004.12.061

Reference yield:

: 75-11-6
diiodomethane

: 108221-59-6
6,7-hydroxy-8-methoxycoumarin

: 81558-03-4
8-methoxy-6,7-methylenedioxycoumarin

Guidance literature:: With sodium hydride; Yield given. Multistep reaction; 1.) HMPT, room temp.; 2.) room temp., 20 min;
DOI:10.1055/s-1986-31796