1,2-dipalmitoyl-3-O-(6'-amino-2',3',4'-tri-O-benzyl-6'-deoxy-α-D-glucosyl)-sn-glycerol

Base Information

• Chemical Name: 1,2-dipalmitoyl-3-O-(6'-amino-2',3',4'-tri-O-benzyl-6'-deoxy-α-D-glucosyl)-sn-glycerol
• CAS No.: 1192755-06-8
• Molecular Formula: C₆₂H₉₇NO₉
• Molecular Weight: 1000.45
• Mol file: 1192755-06-8.mol

Synonyms:1,2-dipalmitoyl-3-O-(6'-amino-2',3',4'-tri-O-benzyl-6'-deoxy-α-D-glucosyl)-sn-glycerol

Chemical Property of 1,2-dipalmitoyl-3-O-(6'-amino-2',3',4'-tri-O-benzyl-6'-deoxy-α-D-glucosyl)-sn-glycerol

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 1,2-dipalmitoyl-3-O-(6'-amino-2',3',4'-tri-O-benzyl-6'-deoxy-α-D-glucosyl)-sn-glycerol

There total 13 articles about 1,2-dipalmitoyl-3-O-(6'-amino-2',3',4'-tri-O-benzyl-6'-deoxy-α-D-glucosyl)-sn-glycerol which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 95.0%

1,2-dipalmitoyl-3-O-(6'-azido-2',3',4'-tri-O-benzyl-6'-deoxy-α-D-glucosyl)-sn-glycerol (1192755-05-7) → 1,2-dipalmitoyl-3-O-(6'-amino-2',3',4'-tri-O-benzyl-6'-deoxy-α-D-glucosyl)-sn-glycerol (1192755-06-8)

Guidance literature:

1,2-dipalmitoyl-3-O-(6'-azido-2',3',4'-tri-O-benzyl-6'-deoxy-α-D-glucosyl)-sn-glycerol; With triphenylphosphine; In tetrahydrofuran; at 20 ℃; for 24h; Inert atmosphere;

With water; In tetrahydrofuran; at 20 ℃; for 24h; Inert atmosphere;

DOI:10.1016/j.carres.2009.05.022

Reference yield:

3-O-(6'-azido-2',3',4'-tri-O-benzyl-6'-deoxy-α-D-glucopyranosyl)-sn-glycerol (1192755-04-6) → 1,2-dipalmitoyl-3-O-(6'-amino-2',3',4'-tri-O-benzyl-6'-deoxy-α-D-glucosyl)-sn-glycerol (1192755-06-8)

Guidance literature:

Multi-step reaction with 2 steps

1: dicyclohexyl-carbodiimide / 4 h / 50 °C

2: triphenylphosphine / tetrahydrofuran / 24 h / 20 °C

With dicyclohexyl-carbodiimide; triphenylphosphine; In tetrahydrofuran;

DOI:10.1016/j.ejmech.2012.06.007

Reference yield:

C33H39N3O7 → 1,2-dipalmitoyl-3-O-(6'-amino-2',3',4'-tri-O-benzyl-6'-deoxy-α-D-glucosyl)-sn-glycerol (1192755-06-8)

Guidance literature:

Multi-step reaction with 3 steps

1: toluene-4-sulfonic acid / methanol

2: pyridine; dmap

3: hydrogen; palladium 10% on activated carbon / methanol; ethyl acetate

With pyridine; dmap; palladium 10% on activated carbon; hydrogen; toluene-4-sulfonic acid; In methanol; ethyl acetate;

DOI:10.3390/md14060116

upstream raw materials:

1,2-dipalmitoyl-3-O-(6'-azido-2',3',4'-tri-O-benzyl-6'-deoxy-α-D-glucosyl)-sn-glycerol

3-O-(6'-azido-2',3',4'-tri-O-benzyl-6'-deoxy-α-D-glucopyranosyl)-sn-glycerol

3-O-(6'-azido-2',3',4'-tri-O-benzyl-6'-deoxy-α-D-glucopyranosyl)-1,2-O-isopropylidene-sn-glycerol

(2R,3R,4S,5R,6S)-2-Azidomethyl-3,4,5-tris-benzyloxy-6-methoxy-tetrahydro-pyran

Downstream raw materials:

1,2-di-O-palmitoyl-3-O-(N-palmitoyl-6'-amino-2',3',4'-tri-O-benzyl-6'-deoxy-α-D-glucopyranosyl)-sn-glycerol