(S)-2-(9H-Fluoren-9-ylmethoxycarbonylamino)-pentanedioic acid 5-tert-butyl ester 1-[4-(2,4-dichloro-phenoxycarbonylmethoxy)-benzyl] ester

Base Information

Chemical Name:(S)-2-(9H-Fluoren-9-ylmethoxycarbonylamino)-pentanedioic acid 5-tert-butyl ester 1-[4-(2,4-dichloro-phenoxycarbonylmethoxy)-benzyl] ester
CAS No.:126771-44-6
Molecular Formula:C₃₉H₃₇Cl₂NO₉
Molecular Weight:734.63
Hs Code.:

Synonyms:(S)-2-(9H-Fluoren-9-ylmethoxycarbonylamino)-pentanedioic acid 5-tert-butyl ester 1-[4-(2,4-dichloro-phenoxycarbonylmethoxy)-benzyl] ester

Suppliers and Price of (S)-2-(9H-Fluoren-9-ylmethoxycarbonylamino)-pentanedioic acid 5-tert-butyl ester 1-[4-(2,4-dichloro-phenoxycarbonylmethoxy)-benzyl] ester

Supply Marketing:

Business phase:: The product has achieved commercial mass production^*data from LookChem market partment

Manufacturers and distributors:

Manufacture/Brand
Chemicals and raw materials
Packaging
price

Total 0 raw suppliers

Chemical Property of (S)-2-(9H-Fluoren-9-ylmethoxycarbonylamino)-pentanedioic acid 5-tert-butyl ester 1-[4-(2,4-dichloro-phenoxycarbonylmethoxy)-benzyl] ester

Chemical Property:

Purity/Quality:

Safty Information:

Pictogram(s):
Hazard Codes:

MSDS Files:

Useful:

Technology Process of (S)-2-(9H-Fluoren-9-ylmethoxycarbonylamino)-pentanedioic acid 5-tert-butyl ester 1-[4-(2,4-dichloro-phenoxycarbonylmethoxy)-benzyl] ester

There total 3 articles about (S)-2-(9H-Fluoren-9-ylmethoxycarbonylamino)-pentanedioic acid 5-tert-butyl ester 1-[4-(2,4-dichloro-phenoxycarbonylmethoxy)-benzyl] ester which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 84.0%

: 71989-18-9
Fmoc-Glu(OtBu)-OH

: 126771-40-2
2,4-dichlorophenyl-4-bromomethyl-phenoxyacetate

: 126771-44-6
(S)-2-(9H-Fluoren-9-ylmethoxycarbonylamino)-pentanedioic acid 5-tert-butyl ester 1-[4-(2,4-dichloro-phenoxycarbonylmethoxy)-benzyl] ester

Guidance literature:: With N-ethyl-N,N-diisopropylamine; In N,N-dimethyl-formamide; for 3h; Ambient temperature;
DOI:10.1016/S0040-4039(00)99355-9

Reference yield:

: 940-64-7
2-(4-methylphenoxy)acetic acid

: 126771-44-6
(S)-2-(9H-Fluoren-9-ylmethoxycarbonylamino)-pentanedioic acid 5-tert-butyl ester 1-[4-(2,4-dichloro-phenoxycarbonylmethoxy)-benzyl] ester

Guidance literature:: Multi-step reaction with 3 steps

1: 55 percent / N-bromosuccinimide, 2,2'-azobisisobutyronitrile / CHCl₃ / Heating

2: 85 percent / dicyclohexylcarbodiimide / ethyl acetate / 0 °C

3: 84 percent / diisopropylethylamine / dimethylformamide / 3 h / Ambient temperature

With N-Bromosuccinimide; 2,2'-azobis(isobutyronitrile); N-ethyl-N,N-diisopropylamine; dicyclohexyl-carbodiimide; In chloroform; ethyl acetate; N,N-dimethyl-formamide;
DOI:10.1016/S0040-4039(00)99355-9

Reference yield:

: 126771-41-3
4-bromomethylphenoxyacetic acid

: 126771-44-6
(S)-2-(9H-Fluoren-9-ylmethoxycarbonylamino)-pentanedioic acid 5-tert-butyl ester 1-[4-(2,4-dichloro-phenoxycarbonylmethoxy)-benzyl] ester

Guidance literature:: Multi-step reaction with 2 steps

1: 85 percent / dicyclohexylcarbodiimide / ethyl acetate / 0 °C

2: 84 percent / diisopropylethylamine / dimethylformamide / 3 h / Ambient temperature

With N-ethyl-N,N-diisopropylamine; dicyclohexyl-carbodiimide; In ethyl acetate; N,N-dimethyl-formamide;
DOI:10.1016/S0040-4039(00)99355-9