2,3,4-tri-O-benzyl-6-O-(2,3,4,6-tetra-O-benzyl-α-D-glucopyranosyl)-α-D-glucopyranosyl trichloroacetimidate

Base Information

• Chemical Name: 2,3,4-tri-O-benzyl-6-O-(2,3,4,6-tetra-O-benzyl-α-D-glucopyranosyl)-α-D-glucopyranosyl trichloroacetimidate
• CAS No.: 136310-60-6
• Molecular Formula: C₆₃H₆₄Cl₃NO₁₁
• Molecular Weight: 1117.56
• Mol file: 136310-60-6.mol

Synonyms:2,3,4-tri-O-benzyl-6-O-(2,3,4,6-tetra-O-benzyl-α-D-glucopyranosyl)-α-D-glucopyranosyl trichloroacetimidate

Chemical Property of 2,3,4-tri-O-benzyl-6-O-(2,3,4,6-tetra-O-benzyl-α-D-glucopyranosyl)-α-D-glucopyranosyl trichloroacetimidate

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2,3,4-tri-O-benzyl-6-O-(2,3,4,6-tetra-O-benzyl-α-D-glucopyranosyl)-α-D-glucopyranosyl trichloroacetimidate

There total 3 articles about 2,3,4-tri-O-benzyl-6-O-(2,3,4,6-tetra-O-benzyl-α-D-glucopyranosyl)-α-D-glucopyranosyl trichloroacetimidate which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield:

benzyl bromide (100-39-0) → 2,3,4-tri-O-benzyl-6-O-(2,3,4,6-tetra-O-benzyl-α-D-glucopyranosyl)-α-D-glucopyranosyl trichloroacetimidate (136310-60-6)

Guidance literature:

Multi-step reaction with 3 steps

1: 1) sodium hydride / 1) DMF, 1 h, RT, 2) RT, overnight

2: 0.62 g / palladium chloride, sodium acetate / acetic acid; H₂O / Ambient temperature

3: sodium hydride / CH₂Cl₂ / 2 h / Ambient temperature

With sodium acetate; sodium hydride; palladium dichloride; In dichloromethane; water; acetic acid;

DOI:10.1016/0008-6215(91)84013-5

Reference yield:

allyl O-(2,3,4,6-tetra-O-benzyl-α-D-glucopyranosyl)-(1<*>6)-2,3,4-tri-O-benzyl-β-D-glucopyranoside (136310-59-3) → 2,3,4-tri-O-benzyl-6-O-(2,3,4,6-tetra-O-benzyl-α-D-glucopyranosyl)-α-D-glucopyranosyl trichloroacetimidate (136310-60-6)

Guidance literature:

Multi-step reaction with 2 steps

1: 0.62 g / palladium chloride, sodium acetate / acetic acid; H₂O / Ambient temperature

2: sodium hydride / CH₂Cl₂ / 2 h / Ambient temperature

With sodium acetate; sodium hydride; palladium dichloride; In dichloromethane; water; acetic acid;

DOI:10.1016/0008-6215(91)84013-5

Reference yield:

O-(2,3,4,6-tetra-O-benzyl-α-D-glucopyranosyl)-(1<*>6)-2,3,4-tri-O-benzyl-D-glucopyranose + trichloroacetonitrile (545-06-2) → 2,3,4-tri-O-benzyl-6-O-(2,3,4,6-tetra-O-benzyl-α-D-glucopyranosyl)-α-D-glucopyranosyl trichloroacetimidate (136310-60-6)

Guidance literature:

With sodium hydride; In dichloromethane; for 2h; Yield given; Ambient temperature;

DOI:10.1016/0008-6215(91)84013-5

upstream raw materials:

trichloroacetonitrile

benzyl bromide

allyl O-(2,3,4,6-tetra-O-benzyl-α-D-glucopyranosyl)-(1<*>6)-2,3,4-tri-O-benzyl-β-D-glucopyranoside

Downstream raw materials:

<2,3-di-O-acetyl-6-O-(2,3,4,2',3',4',6'-hepta-O-benzyl-isomaltosyl)>hexakis(2,3,6-tri-O-acetyl)-β-CD