(±)-2-[[3-acetyl-1-(o-tolylmethyl)pyridin-1-ium-4-yl]methyl]-5,6-dimethoxy-indan-1-one bromide

Base Information

Chemical Name:(±)-2-[[3-acetyl-1-(o-tolylmethyl)pyridin-1-ium-4-yl]methyl]-5,6-dimethoxy-indan-1-one bromide
CAS No.:1620645-59-1
Molecular Formula:Br*C₂₇H₂₈NO₄
Molecular Weight:510.428
Hs Code.:

Synonyms:(±)-2-[[3-acetyl-1-(o-tolylmethyl)pyridin-1-ium-4-yl]methyl]-5,6-dimethoxy-indan-1-one bromide

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Chemical Property of (±)-2-[[3-acetyl-1-(o-tolylmethyl)pyridin-1-ium-4-yl]methyl]-5,6-dimethoxy-indan-1-one bromide

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Technology Process of (±)-2-[[3-acetyl-1-(o-tolylmethyl)pyridin-1-ium-4-yl]methyl]-5,6-dimethoxy-indan-1-one bromide

There total 6 articles about (±)-2-[[3-acetyl-1-(o-tolylmethyl)pyridin-1-ium-4-yl]methyl]-5,6-dimethoxy-indan-1-one bromide which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 63.0%

: 1620646-04-9
3-(1-acetyl)-4-(5,6-dimethoxy-1-oxo-2,3-dihydro-1H-inden-2-yl)methylpyridine

: 89-92-9
2-methylbenzyl bromide

: 1620645-59-1
(±)-2-[[3-acetyl-1-(o-tolylmethyl)pyridin-1-ium-4-yl]methyl]-5,6-dimethoxy-indan-1-one bromide

Guidance literature:: In dichloromethane; for 12h; Reflux;
DOI:10.1021/acs.jmedchem.7b00702

Reference yield: 63.0%

: 1620645-59-1
(±)-2-[[3-acetyl-1-(o-tolylmethyl)pyridin-1-ium-4-yl]methyl]-5,6-dimethoxy-indan-1-one bromide

Guidance literature:: In dichloromethane; for 12h; Reflux; Sealed tube;

Reference yield:

: 1620646-33-4
(2E)-2-[(3-bromo-4-pyridyl)methylene]-5,6-dimethoxy-indan-1-one

: 1620645-59-1
(±)-2-[[3-acetyl-1-(o-tolylmethyl)pyridin-1-ium-4-yl]methyl]-5,6-dimethoxy-indan-1-one bromide

Guidance literature:: Multi-step reaction with 3 steps

1: hydrogen; 5 % platinum on carbon / ethanol / 3 h / 20 °C / 760.05 Torr / Reflux; Dean-Stark

2: bis(dibenzylideneacetone)-palladium⁽⁰⁾; triphenylphosphine / toluene / 110 °C

3: dichloromethane / 12 h / Reflux

With 5 % platinum on carbon; hydrogen; triphenylphosphine; bis(dibenzylideneacetone)-palladium⁽⁰⁾; In ethanol; dichloromethane; toluene;
DOI:10.1021/acs.jmedchem.7b00702