2-fluoro-5-iodobenzaldehyde oxime

Base Information

• Chemical Name: 2-fluoro-5-iodobenzaldehyde oxime
• CAS No.: 334971-55-0
• Molecular Formula: C₇H₅FINO
• Molecular Weight: 265.026
• Mol file: 334971-55-0.mol

Synonyms:2-fluoro-5-iodobenzaldehyde oxime

Chemical Property of 2-fluoro-5-iodobenzaldehyde oxime

Chemical Property:

Purity/Quality:

Safty Information:

• Pictogram(s):  
• Hazard Codes: 

MSDS Files:

Useful:

Technology Process of 2-fluoro-5-iodobenzaldehyde oxime

There total 1 articles about 2-fluoro-5-iodobenzaldehyde oxime which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 78.0%

2-Fluoro-5-iodo-benzaldehyde (146137-76-0) → 2-fluoro-5-iodobenzaldehyde oxime (334971-55-0)

Guidance literature:

2-Fluoro-5-iodo-benzaldehyde; With sodium hydroxide; hydroxylamine hydrochloride; In ethanol; water; at 25 - 30 ℃; for 2h; Ice cooling; Stirring;

With hydrogenchloride; In ethanol; water; at 25 - 30 ℃; pH=4;

Reference yield:

2-fluoro-5-iodobenzaldehyde oxime (334971-55-0) → 2-fluoro-5-iodobenzoyl chloride oxime (334971-56-1)

Guidance literature:

With hydrogenchloride; N-chloro-succinimide; In DMF (N,N-dimethyl-formamide); at 25 - 40 ℃; for 2h;

Reference yield:

2-fluoro-5-iodobenzaldehyde oxime (334971-55-0) + hydroxy-1-propyne (6175-54-8) → C10H7FINO2

Guidance literature:

2-fluoro-5-iodobenzaldehyde oxime; hydroxy-1-propyne; With N-chloro-succinimide; In dichloromethane; for 0.5h; Reflux;

With triethylamine; In dichloromethane; for 4h; Reflux;

DOI:10.1016/j.bmcl.2017.04.039

upstream raw materials:

2-Fluoro-5-iodo-benzaldehyde

Downstream raw materials:

2-fluoro-5-iodobenzoyl chloride oxime

Refernces

• 1、 -. "Compounds and method for inhibiting MRP1". Page column 55. . Retrieved 2010/02/05.