2,4,6-tris(3,5-diisopropylphenyl)cyclotriboroxane

Base Information

• Chemical Name: 2,4,6-tris(3,5-diisopropylphenyl)cyclotriboroxane
• CAS No.: 906623-14-1
• Molecular Formula: C₃₆H₅₁B₃O₃
• Molecular Weight: 564.232
• Mol file: 906623-14-1.mol

Synonyms:2,4,6-tris(3,5-diisopropylphenyl)cyclotriboroxane

Chemical Property of 2,4,6-tris(3,5-diisopropylphenyl)cyclotriboroxane

Chemical Property:

Purity/Quality:

Safty Information:

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• Hazard Codes: 

MSDS Files:

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Technology Process of 2,4,6-tris(3,5-diisopropylphenyl)cyclotriboroxane

There total 6 articles about 2,4,6-tris(3,5-diisopropylphenyl)cyclotriboroxane which guide to synthetic route it. The literature collected by LookChem mainly comes from the sharing of users and the free literature resources found by Internet computing technology. We keep the original model of the professional version of literature to make it easier and faster for users to retrieve and use. At the same time, we analyze and calculate the most feasible synthesis route with the highest yield for your reference as below:

synthetic route:

Reference yield: 66.0%

1-bromo-3,5-bis(propan-2-yl)benzene (23058-81-3) → 2,4,6-tris(3,5-diisopropylphenyl)cyclotriboroxane (906623-14-1) + (3,5-diisopropylphenyl)boronic acid (263397-82-6)

Guidance literature:

With n-butyllithium; boric acid tributyl ester; N,N,N,N,-tetramethylethylenediamine; In tetrahydrofuran; diethyl ether; at -78 - 20 ℃; for 1.33333h;

DOI:10.1002/ejoc.200600030

Reference yield:

4-bromo-2,6-diisopropylaniline (80058-84-0) → 2,4,6-tris(3,5-diisopropylphenyl)cyclotriboroxane (906623-14-1)

Guidance literature:

Multi-step reaction with 2 steps

1.1: NaNO₂ / aq. HCl / -5 °C

1.2: 82 percent / aq. H₃PO₄ / 48 h / 4 - 20 °C

2.1: 66 percent / TMEDA; nBuLi; B(OBu)3 / tetrahydrofuran; diethyl ether / 1.33 h / -78 - 20 °C

With n-butyllithium; boric acid tributyl ester; N,N,N,N,-tetramethylethylenediamine; sodium nitrite; In tetrahydrofuran; hydrogenchloride; diethyl ether;

DOI:10.1002/ejoc.200600030

Reference yield:

4-bromo-2,6-diisopropylaniline (80058-84-0) → 2,4,6-tris(3,5-diisopropylphenyl)cyclotriboroxane (906623-14-1) + (3,5-diisopropylphenyl)boronic acid (263397-82-6)

Guidance literature:

Multi-step reaction with 2 steps

1.1: sodium nitrite; hydrogenchloride / water / 0.17 h / -10 °C / Inert atmosphere

1.2: 48 h / 20 °C / Inert atmosphere

2.1: N,N,N,N,-tetramethylethylenediamine; n-butyllithium / diethyl ether / 1 h / -78 °C / Inert atmosphere

2.2: 10 h / 20 °C / Inert atmosphere

2.3: Inert atmosphere

With hydrogenchloride; n-butyllithium; N,N,N,N,-tetramethylethylenediamine; sodium nitrite; In diethyl ether; water;

DOI:10.1021/acs.inorgchem.7b02276

upstream raw materials:

1-bromo-3,5-bis(propan-2-yl)benzene

2,6-diisopropylbenzenamine

4-bromo-2,6-diisopropylaniline

boric acid tributyl ester

Downstream raw materials:

3,5-diisopropylphenol