Technology Process of (1R)-(-)-1,2,3-tri-O-acetyl-(1,3/2,4,6)-4-bromo-6-bromomethyl-1,2,3-cyclohexanetriol
There total 3 articles about (1R)-(-)-1,2,3-tri-O-acetyl-(1,3/2,4,6)-4-bromo-6-bromomethyl-1,2,3-cyclohexanetriol which
guide to synthetic route it.
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synthetic route:
- Guidance literature:
-
With
hydrogen bromide;
In
acetic acid;
at 85 ℃;
for 20h;
DOI:10.1039/P19850000903
- Guidance literature:
-
Multi-step reaction with 3 steps
1: 66 percent / 90percent formic acid, 35percent hydrogen peroxide / 0.33 h / 70 °C
2: 1) lithium aluminium hydride / 1) THF, RT, 30 min, 2) pyridine, RT, 1 h
3: 53 percent / 20percent hydrogen bromide / acetic acid / 20 h / 85 °C
With
lithium aluminium tetrahydride; formic acid; hydrogen bromide; dihydrogen peroxide;
In
acetic acid;
DOI:10.1039/P19850000903
- Guidance literature:
-
Multi-step reaction with 2 steps
1: 1) lithium aluminium hydride / 1) THF, RT, 30 min, 2) pyridine, RT, 1 h
2: 53 percent / 20percent hydrogen bromide / acetic acid / 20 h / 85 °C
With
lithium aluminium tetrahydride; hydrogen bromide;
In
acetic acid;
DOI:10.1039/P19850000903